Preparing clinically expert faculty educators: an academic partnership model.

To increase nursing education capacity in New Jersey, the Robert Wood Johnson Foundation (RWJF) New Jersey Nursing Initiative (NJNI) awarded grants to prepare graduate nursing students to become clinically expert faculty. The purpose of this article was to describe the experiences of a collaborative partnership in preparing 14 scholars for the faculty role. The partnership developed two innovative models of preparing faculty with clinical expertise.

Types of abuse.

The four most common types of abuse are physical, sexual, emotional, and economic. Abuse is often further categorized into child abuse, intimate partner violence, and elder abuse. This article describes the important role that nurses and health care providers play in detecting, assessing, and reporting abuse.

Correlates of sexual dysfunction in men and women with multiple sclerosis.

Sexual dysfunction (SD) is an often overlooked disability in multiple sclerosis (MS). The purpose of this study was to investigate the relationship between SD and other disabilities in men and women with MS. The sample included 32 men and 219 women.

Endogenous kappa-opioid receptor systems inhibit hyperalgesia associated with localized peripheral inflammation.

Peripheral inflammation evokes functional and biochemical changes in the periphery and spinal cord which result in central sensitization and hypersensitivity. Inhibitory control systems from the rostral ventromedial medulla (RVM) are also activated. The present study investigates whether endogenous kappa-opioid receptor (KOPr) systems contribute to these neuroadaptations.

The effects of local perfusion of DAMGO on extracellular GABA and glutamate concentrations in the rostral ventromedial medulla.

Electrophysiological data suggest an involvement of rostral ventromedial medulla (RVM) GABA and glutamate (GLU) neurons in morphine analgesia. Direct evidence that extracellular concentrations of GABA or GLU are altered in response to mu opioid receptor (MOP-R) activation is, however, lacking. We used in vivo microdialysis to investigate this issue.

Inflammation-induced changes in rostral ventromedial medulla mu and kappa opioid receptor mediated antinociception.

Acute microinjection of mu-, delta-, or kappa-opioid receptor (MOPr, DOPr, KOPr) agonists into the rostral ventromedial medulla (RVM) produces antinociception. Thermal antinociception produced by MOPr and DOPr agonists is potentiated during inflammation [Hurley RW, Hammond DL. The analgesic effects of supraspinal mu and delta opioid receptor agonists are potentiated during persistent inflammation.