Publications by authors named "Janet L Jones"

Article Synopsis
  • Integrin alpha3beta1 helps cells stick to a protein called laminin, which is important for blood vessels and can change when tumors grow.
  • Scientists created special mice to study the effects of removing alpha3 from blood vessel cells, and found that these mice had bigger tumors and more new blood vessel growth.
  • The research shows that alpha3beta1 helps control the growth of blood vessels, and that a little bit of a protein called VEGF from these cells can actually prevent other signals that tell blood vessels to grow too much.
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Families often draw their conclusions about the quality of care received by a family member during the last months of life from their interactions with professional caregivers. A more comprehensive understanding of how these relationships influence the care experience should include an investigation of the association between employee job satisfaction and family perception of the quality of care. This cross-sectional study investigated the association at a regional hospice.

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Objectives: Superficial bladder cancer (SBC) presents a difficult clinical dilemma at diagnosis as only a small subgroup of patients will subsequently develop invasive disease. Study of cancer biology has found that angiogenesis is central to growth and spread. This study examines the relationship between the angiogenic inhibitory factor Thrombospondin-1 (TSP-1) at initial presentation and subsequent progression of SBC.

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