Publications by authors named "Janet Freeman-Daily"

Article Synopsis
  • The purpose of this guideline is to provide updated, evidence-based treatment recommendations for patients with stage IV non-small cell lung cancer (NSCLC) who do not have specific genetic driver alterations.
  • The recommendations are based on recent systematic reviews and randomized clinical trials, focusing on both efficacy and safety, and were developed by an Expert Panel with diverse expertise.
  • The latest update identified ten new randomized clinical trials and consolidates previous recommendations, covering treatment options for first, second, and subsequent lines of therapy.
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Article Synopsis
  • The guideline aims to provide evidence-based recommendations for treating stage IV non-small cell lung cancer patients with specific driver alterations.
  • It is regularly updated based on systematic reviews of clinical trials, with the latest review covering studies from February to October 2023.
  • The latest update identified eight new randomized controlled trials and refined treatment recommendations for different stages of therapy based on targetable driver alterations.
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Purpose: Patients who have cancer have leveraged the Internet to gain a better understanding of their disease and connect across geographic boundaries with others facing the same challenges. Online cancer communities have developed into resources that highlight new research and evolving care pathways. Combined with increasing health literacy and social media, they have enabled some patients to become experts in their cancer.

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Background: An ASCO taskforce comprised of representatives of oncology clinicians, the American Cancer Society National Lung Cancer Roundtable (NLCRT), LUNGevity, the GO Foundation for Lung Cancer, and the ROS1ders sought to: characterize U.S. oncologists' biomarker ordering and treatment practices for advanced non-small-cell lung cancer (NSCLC); ascertain barriers to biomarker testing; and understand the impact of delays on treatment decisions.

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Although precision medicine has had a mixed impact on the clinical management of patients with advanced-stage cancer overall, for NSCLC, and more specifically for lung adenocarcinoma, the advances have been dramatic, largely owing to the genomic complexity and growing number of druggable oncogene drivers. Furthermore, although tumor tissue is historically the "accepted standard" biospecimen for these molecular analyses, there are considerable innate limitations. Thus, liquid biopsy represents a practical alternative source for investigating tumor-derived somatic alterations.

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Purpose: The discovery of driver oncogenes, such as , has led to the development of targeted therapies. Despite clinical advancements, gaps remain in our understanding of characteristics of patients with -positive () cancers. The purpose of this study was to comprehensively assess demographic, clinical, and environmental characteristics associated with cancers worldwide.

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Twitter use has increased among patients with cancer, advocates, and oncology professionals. Hashtags, a form of metadata, can be used to share content, organize health information, and create virtual communities of interest. Cancer-specific hashtags modeled on a breast cancer community, #bcsm, led to the development of a structured set of hashtags called the cancer tag ontology.

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The art of practicing oncology has evolved substantially in the past 5 years. As more and more diagnostic tests, biomarker-directed therapies, and immunotherapies make their way to the oncology marketplace, oncologists will find it increasingly difficult to keep up with the many therapeutic options. Additionally, the cost of cancer care seems to be increasing.

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