Publications by authors named "Janet E Brouwer"
Int J Cardiol Heart Vasc
August 2023
Article Synopsis
- A study was conducted to evaluate the effectiveness of macitentan, an endothelin-1 receptor inhibitor, in treating patients with angina caused by coronary artery spasm (CAS) who continued to experience symptoms despite standard treatment.
- 28 participants (mainly women, average age 55) were given either macitentan or a placebo for four weeks, followed by a switch, measuring changes in anginal burden during each phase.
- Results showed no significant difference in anginal burden between macitentan and placebo, and the frequency and severity of side effects were similar for both treatments.
