Complete Chloroplast Genome of an Endophytic sp. (Ostreobiaceae) from the U.S. Virgin Islands.

We present the complete chloroplast genome sequence of an endophytic sp. isolated from a 19th-century coralline red algal specimen from St. Croix, U.

Perineal Rectosigmoidectomy (Altemeier Procedure) as Treatment of Strangulated Rectal Prolapse.

Incarceration of a rectal prolapse is an unusual entity that represents a surgical emergency. Even more rarely, it becomes strangulated, requiring emergency surgery. When surgery becomes inevitable, the choice of procedure varies.

A benchmark survey of the common plants of South Northumberland and Durham, United Kingdom.

Background: It is obvious to anyone studying plants in the landscape that man-made environmental change is having profound effects on the abundance, distribution and composition of plant communities. Nevertheless, quantifying these changes and estimating the impact of the different drivers of change is extremely difficult. Botanical surveying can potentially provide insights to the changes that are occurring and inform decisions related to conservation, agriculture and forestry policy.

Treatment of chronic nonhealing neurotrophic corneal epithelial defects with thymosin beta4.

Neurotrophic corneal defects are difficult to heal and all too often lead to scarring and vision loss. Medical management is often of limited success. We describe the results of nine patients (ages 37-84) with chronic nonhealing neurotrophic corneal epithelial defects who were treated with thymosin beta 4 (Tbeta4) sterile eye drops for 28 or 49 days with a follow-up period of 30 days.

Thymosin beta4: structure, function, and biological properties supporting current and future clinical applications.

Published studies have described a number of physiological properties and cellular functions of thymosin beta4 (Tbeta4), the major G-actin-sequestering molecule in mammalian cells. Those activities include the promotion of cell migration, blood vessel formation, cell survival, stem cell differentiation, the modulation of cytokines, chemokines, and specific proteases, the upregulation of matrix molecules and gene expression, and the downregulation of a major nuclear transcription factor. Such properties have provided the scientific rationale for a number of ongoing and planned dermal, corneal, cardiac clinical trials evaluating the tissue protective, regenerative and repair potential of Tbeta4, and direction for future clinical applications in the treatment of diseases of the central nervous system, lung inflammatory disease, and sepsis.