Publications by authors named "Janelle L Grimes"
Article Synopsis
- Early synaptogenesis in the calyx of Held, a large nerve terminal in the mammalian CNS, shows rapid growth and development before the onset of hearing.
- Functional assessments indicate a dramatic increase in postsynaptic currents between postnatal days 1 and 4, alongside significant structural changes such as increased postsynaptic densities.
- The study reveals that the calyces exhibit rare convergence on postsynaptic targets during early development, suggesting a unique process for establishing connections that deviates from typical synapse formation patterns.
An analysis of the development of human papillomavirus (HPV) vaccines requires a fundamental comprehension of the underlying science of the technology, as well as an appreciation for the business issues essential to successful commercialization. Students analyzing this topic must consider scientific challenges related to the development of these vaccines, as well as the implications for their commercialization. This case study describes the evolution of our understanding of HPV infection and its causative link to cervical cancer, the establishment of viable HPV vaccine candidates, and various issues related to HPV vaccine implementation.
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