Publications by authors named "Janel M Peterson"
Genes (Basel)
January 2020
Article Synopsis
- - eNAD/EDM is a hereditary neurodegenerative disease in horses associated with vitamin E deficiency, showing neurological signs in their first year of life.
- - A study using 670,000 SNP markers identified two significant genetic markers on ECA7 linked to the disease, and caytaxin was initially considered a potential candidate gene due to its role in ataxia in mouse models.
- - Further analysis revealed that the variants related to caytaxin were not associated with the disease phenotype, and despite vitamin E supplementation in mice, it did not improve symptoms, leading to its exclusion as a candidate gene.
