Publications by authors named "Jane Rose Paccard"

Article Synopsis
  • A cohort study named Amber was conducted in France to gather real-life data on biliary tract cancer (BTC) treatment between 2019 and 2021, focusing on clinical practices and patient outcomes.
  • The study included 138 patients, mostly with locally advanced or metastatic BTC, highlighting their demographics, treatment responses, and overall survival statistics.
  • Results indicated that a majority of patients received first-line palliative chemotherapy, with 23% showing an objective response and a median overall survival of 13.4 months, aligning well with international treatment guidelines and existing research.
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Background & Aims: Accumulating data has shown the rising incidence and poor prognosis of early-onset gastrointestinal cancers, but few data exist on biliary tract cancers (BTC). We aimed to analyse the clinico-pathological, molecular, therapeutic characteristics and prognosis of patients with early onset BTC (EOBTC, age ≤50 years at diagnosis), versus olders.

Methods: We analysed patients diagnosed with intrahepatic cholangiocarcinoma, extrahepatic cholangiocarcinoma, and gallbladder adenocarcinoma between 1 January 2003 and 30 June 2021.

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