Publications by authors named "Jane Namugga"

Article Synopsis
  • - External beam radiotherapy (EBRT) was unavailable in Uganda for nearly two years, leading to the development of a new treatment strategy involving neoadjuvant chemotherapy (NAC) for bulky cervical cancer patients.
  • - A study of 53 patients found that 75.5% completed the NAC protocol, with most receiving a platinum-taxane combination, and reported adverse events were mostly mild hematologic issues.
  • - The findings suggest that even in a resource-limited setting, most patients successfully completed NAC with manageable side effects, and some went on to receive surgery and adjuvant therapy as needed.
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Background: In Uganda, cervical cancer (CaCx) is the commonest cancer, accounting for 35.7% of all cancer cases in women. The rates of human papillomavirus vaccination and CaCx screening remain low.

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Objectives: This study aimed to report the proportion of women with a new diagnosis of cervical cancer recommended for curative hysterectomy as well as associated factors. We also report recommended treatments by stage and patterns of treatment initiation.

Design: This was an observational cohort study.

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There is significant disparity in the prevalence of cervical cancer globally, with low- and middle-income countries (LMICs) shouldering a disproportionate share of disease incidence and an even greater proportion of morbidity and mortality. Available resources for diagnosis, treatment and palliation of cervical cancer are inversely related to per capita income. While prevention and screening remain public health priorities, given the large number of women affected by cervical cancer, expanding treatment capacity should be included in any evidence-based intervention plan.

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