Publications by authors named "Jane Musumali"
Penile squamous cell carcinoma (PSCC) occurs more frequently in some developing countries compared to developed countries. Infection with HIV and/or high-risk human papillomavirus (hrHPV) are risk factors for penile cancer development. The tumor microenvironment of PSCC may predict prognosis and may inform on the best targets for immunotherapy.
View Article and Find Full Text PDFKaposi sarcoma (KS), a multifocal vascular neoplasm frequently observed in HIV-positive individuals, primarily affects the skin, mucous membranes, visceral organs, and lymph nodes. KS is associated primarily with Kaposi sarcoma-associated herpesvirus (KSHV) infection. In this case report, we present a rare occurrence of co-infection and co-localization of KSHV and Epstein-Barr virus (EBV) in KS arising from the conjunctiva, which, to our knowledge, has not been reported previously.
View Article and Find Full Text PDFArticle Synopsis
- The study investigates whether HIV-1 subtype C can be detected in brain tissue, specifically looking at viral load differences across various brain regions in a 38-year-old Zambian woman who died from HIV/AIDS.
- Using advanced PCR techniques on brain tissue samples, the researchers found that 35.9% of tissue blocks contained HIV-1 viral DNA, with the highest concentrations in the basal ganglia and frontal lobe.
- Significant differences in viral load were reported between certain brain regions, indicating a non-uniform distribution of HIV-1 in the brain.