Publications by authors named "Jane Musumali"

Penile squamous cell carcinoma (PSCC) occurs more frequently in some developing countries compared to developed countries. Infection with HIV and/or high-risk human papillomavirus (hrHPV) are risk factors for penile cancer development. The tumor microenvironment of PSCC may predict prognosis and may inform on the best targets for immunotherapy.

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Kaposi sarcoma (KS), a multifocal vascular neoplasm frequently observed in HIV-positive individuals, primarily affects the skin, mucous membranes, visceral organs, and lymph nodes. KS is associated primarily with Kaposi sarcoma-associated herpesvirus (KSHV) infection. In this case report, we present a rare occurrence of co-infection and co-localization of KSHV and Epstein-Barr virus (EBV) in KS arising from the conjunctiva, which, to our knowledge, has not been reported previously.

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Article Synopsis
  • The study investigates whether HIV-1 subtype C can be detected in brain tissue, specifically looking at viral load differences across various brain regions in a 38-year-old Zambian woman who died from HIV/AIDS.
  • Using advanced PCR techniques on brain tissue samples, the researchers found that 35.9% of tissue blocks contained HIV-1 viral DNA, with the highest concentrations in the basal ganglia and frontal lobe.
  • Significant differences in viral load were reported between certain brain regions, indicating a non-uniform distribution of HIV-1 in the brain.
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