Effects of methylprednisolone on inflammatory activity and oxidative stress in the lungs of brain-dead rats.

Objective: To evaluate the effects that early and late systemic administration of methylprednisolone have on lungs in a rat model of brain death.

Methods: Twenty-four male Wistar rats were anesthetized and randomly divided into four groups (n = 6 per group): sham-operated (sham); brain death only (BD); brain death plus methylprednisolone (30 mg/kg i.v.

Immunohistochemical expression of HER-2/NEU-CERBB-2 in patients with adenocarcinoma of the stomach.

Objectives: To determine the prevalence of Her-2/Neu-cerbb-2 in the gastric mucosa of patients with gastric adenocarcinoma in a brazilian patient group.

Methods: The immunohistochemical expression of Her-2/Neu was studied in 37 formalin-fixed paraffin-embedded tissue sections.

Results: The immunohistochemical reaction produced by the anti-HER-2/Neu antibody was positive in two cases (5.

Prevalence study of metastases in cirrhotic livers.

Background/aims: Metastatic carcinoma is rarely seen in cirrhotic livers. The aim of this study is to verify the prevalence of metastases in cirrhotic liver comparing cirrhotic patients with a control group.

Methodology: This study is based on 7,092 necropsies performed in two big Hospitals of Porto Alegre, Brazil.