Performance of statistical models of shape and appearance for semiautomatic segmentations of spinal vertebrae T4-L4 on digitized vertebral fracture assessment images.

Background Context: Despite its clinical importance, accurate identification of vertebral fractures is problematic and time-consuming. There is a recognized need to improve the detection of vertebral fractures so that appropriate high-risk patients can be selected to initiate clinically beneficial therapeutic interventions.

Purpose: To develop and evaluate semiautomatic algorithms for detailed annotation of vertebral bodies from T4 to L4 in digitized lateral spinal dual-energy X-ray absorptiometry (DXA) vertebral fracture assessment (VFA) images.

Methods and reliability of radiographic vertebral fracture detection in older men: the osteoporotic fractures in men study.

We describe the methods and reliability of radiographic vertebral fracture assessment in MrOS, a cohort of community dwelling men aged ≥65yrs. Lateral spine radiographs were obtained at Visit 1 (2000-2) and 4.6years later (Visit 2).

Comprehensive vertebral deformity and vertebral fracture assessment in clinical practice: intra- and inter-reader agreement of a clinical workflow tool.

Study Design: Study design randomized intra- and inter-reader reproducibility study.

Objective: To evaluate reproducibility of quantitative morphometry (QM) and agreement of dichotomous fracture/no-fracture status on lateral spinal radiographs acquired during routine clinical practice using a clinical workflow tool.

Summary Of Background Data: Several recent guidelines have underlined the importance of Genant semi-quantitative scoring and selective QM to confirm and grade suspected vertebral fractures in clinical practice.