Publications by authors named "Jane Dahl Andersen"
Article Synopsis
- Osteogenesis imperfecta (OI) is a hereditary condition characterized by faulty collagen type I, which can affect lung function and increase the risk of respiratory diseases.
- A nationwide study in Denmark compared hospital admission rates for asthma, COPD, and pneumonia between individuals with OI and a reference population from 1995 to 2018.
- Results showed higher admission rates for women over 65 and boys aged 0-18 with OI, indicating a relative increase in hospitalization risk for respiratory issues despite overall low admissions in the OI cohort.
Background: Osteogenesis Imperfecta (OI) is a genetic disease characterized by skeletal fragility. Collagen type 1 is found in many tissues and collagen abnormalities may result in organ specific symptomatology. Musculoskeletal pain is a known issue for patients with OI, osteoarthritis (OA) can be a likely cause.
View Article and Find Full Text PDFEfficient therapies are available for the treatment of osteoporosis, however, there are still unmet needs. Anti-resorptive therapies only increase bone mineral density to a certain extent and reduce the risk of non-vertebral fractures by 20%, only one anabolic option is available in most parts of the world-the effect of which levels off over time, and the evidence for combination therapy targeting both resorption and formation is limited. In addition, identification and treatment of patients with high and imminent fracture risk following a recent fracture and long-term adherence to treatment are 2 other very prominent challenges to the management of osteoporosis.
View Article and Find Full Text PDFBackground And Aim Of The Study: Ischemic mitral regurgitation (IMR) appears in 20-50% of patients after acute myocardial infarction, and entails an increased long-term mortality. In order to compensate for the diversified pathology in humans, this disease entity has been developed in pigs in order to allow investigations of therapeutic options against IMR.
Methods: The left circumflex coronary artery was occluded using catheter-based intracoronary coil deployment in 24 female pigs (body weight 50 kg).