Publications by authors named "Jane D Grundy"
Background: Atopic eczema (AE) is a chronic, itchy, inflammatory skin condition that affects the quality of life of children and their families. The role of specialist clothing in the management of AE is poorly understood.
Objectives: To assess the effectiveness and cost-effectiveness of silk garments for the management of AE in children with moderate to severe disease.
Background: The role of clothing in the management of eczema (also called atopic dermatitis or atopic eczema) is poorly understood. This trial evaluated the effectiveness and cost-effectiveness of silk garments (in addition to standard care) for the management of eczema in children with moderate to severe disease.
Methods And Findings: This was a parallel-group, randomised, controlled, observer-blind trial.
Article Synopsis
- * Undiagnosed wheeze was found in 4.9% of participants at 18 years and was similar in symptom frequency and severity to diagnosed asthma, but with different physiological characteristics and a lower likelihood of atopy.
- * Key risk factors for undiagnosed wheeze included earlier smoking onset, higher rates of smoking and paracetamol use, and a family history of asthma, suggesting a need for better recognition and understanding of this condition for future health implications.