Publications by authors named "Jane Betsy Isaac"
J Mol Histol
October 2024
Article Synopsis
- - The study examined the toxic effects of the ethanolic extract of Passiflora incarnata (EEP) and its nanoformulation (N-EEP) in both lab models, specifically zebrafish embryos and Swiss albino mice, confirming their composition through phytochemical analysis.
- - In vitro tests showed that both EEP and N-EEP affected normal lung cells in a dose-dependent manner, while no developmental issues were seen in zebrafish embryos at a concentration of 200 µg/ml.
- - Acute and sub-acute toxicity tests in mice revealed that doses below 600 mg/kg of EEP and N-EEP can be considered safe for treating various diseases, as evidenced by observed physiological parameters and histopathological analyses
