Publications by authors named "Janan Hishmeh"
Patient Prefer Adherence
January 2017
Article Synopsis
- Opioid-induced constipation (OIC) is a common and challenging side effect of opioid therapy that often does not respond well to standard laxatives.
- New medications called peripherally acting μ-opioid receptor antagonists, like methylnaltrexone, naloxegol, and alvimopan, show promise in treating OIC without interfering with pain relief.
- Alternative treatments also include combinations of oxycodone with naloxone to manage pain while addressing constipation, although some side effects like abdominal pain may occur.
