Publications by authors named "Janam Dave"
Article Synopsis
- Human noroviruses (HuNoVs) are key contributors to diarrhea outbreaks worldwide, and studying them was difficult due to a lack of effective culture methods.
- Recent advancements in cultivating various HuNoV strains in human intestinal enteroids (HIEs) have greatly improved research into their replication and disease mechanisms.
- The research showed that different types of HIEs, particularly those from small intestines and genetically modified lines, have varying levels of susceptibility to HuNoV infection, revealing insights into how these viruses affect human health.
Unlabelled: Human noroviruses (HuNoVs) are a significant cause of epidemic and sporadic acute gastroenteritis worldwide. The lack of a reproducible culture system hindered the study of HuNoV replication and pathogenesis for almost a half-century. This barrier was overcome with our successful cultivation of multiple HuNoV strains in human intestinal enteroids (HIEs), which has significantly advanced HuNoV research.
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