Publications by authors named "Jana Reinhart"
Lancet Psychiatry
December 2024
Article Synopsis
- Antipsychotic polypharmacy, or the use of multiple antipsychotic medications, is common in clinical practice, but it carries a higher risk of side effects and there's little proof that it works better than using a single medication.
- A systematic review analyzed 517 studies involving over 4.4 million individuals to determine the prevalence and trends of antipsychotic polypharmacy across different mental disorders.
- The findings revealed that 24.8% of individuals were using multiple antipsychotics, with higher rates in those with schizophrenia spectrum disorders and significant regional variations, showing an overall trend of increasing polypharmacy from 1970 to 2023.
