Publications by authors named "Jana Nekolova"

Aim: The objective of this study was to evaluate the efficacy of diabetic macular edema (DME) therapy using subthreshold micropulse laser (SMPL) with a wavelength of 577 nm during a long-term monitoring period of 5 years.

Methods: The cohort included the total number of 52 eyes of 34 patients with DME. All underwent the standard laser treatment for the diabetic retinopathy outside the macula and DME treatment with SMPL.

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Introduction: The objective of this prospective study was to evaluate the effects of intraocular macular lens implantation and visual rehabilitation on the quality of life of patients with geographic atrophy (GA) secondary to age-related macular degeneration (AMD).

Methods: Patients with bilaterally decreased near vision (not better than 0.3 logMAR with the best correction), pseudophakia, were included in the project.

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Aims: We present a familial hereditary macular dystrophy, resembling North Carolina Macular Dystrophy. In members of a family, we describe the development of diagnostic-therapeutic approaches and their impact on the prognosis of those whose vision was affected.

Methods: The macular dystrophy of varying degrees of severity was diagnosed in 3 consecutive generations in different family members, both men and women.

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Background: For patients with age-related macular degeneration (AMD), a special intraocular lens implantation partially compensates for the loss in the central part of the visual field. For six months, we evaluated changes in neurophysiological parameters in patients implanted with a "Scharioth macula lens" (SML; a center near high add + 10 D and peripheral plano carrier bifocal lens designed to be located between the iris and an artificial lens).

Methods: Fourteen patients (5 M, 9 F, 63-87 years) with dry AMD were examined prior to and at 3 days after, as well as 1, 2, and 6 months after, implantation using pattern-reversal, motion-onset, and cognitive evoked potentials, psychophysical tests evaluating distant and near visual acuity, and contrast sensitivity.

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Article Synopsis
  • The study reports on the outcomes of implanting a supplementary Scharioth macula lens (SML) in one eye of pseudophakic patients with age-related macular degeneration (AMD).
  • It included 50 patients, all over 55 years old, and showed a significant improvement in near vision (CNVA) after the lens was implanted, with an increase from 0.23 to 0.57 (decimal) within one year.
  • While the procedure was mostly safe, with only one case of postoperative glare, the overall distance vision (CDVA) remained stable, indicating that the SML is effective for improving near vision without adversely affecting distance vision.
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Colletotrichum species are known as important pathogens of plants with an impact on crop production. Some of these species are also known as a cause of rare ophthalmic infections in humans. A case of keratitis caused by Colletotrichum dematium after corneal trauma in a 56-year-old woman is presented.

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Purpose: To evaluate the relationship between the ischemic index and the oxygen saturation in retinal vessels in patients with retinal vein occlusion.

Design: Prospective, cross-sectional study.

Methods: We performed a prospective study.

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Aims: To present the initial results of Scharioth Macula Lens (SML) implantation. The SML is a new add-on intraocular lens designed to increase uncorrected near visual acuity (UCVA) in patients with stabilized maculopathy.

Methods: Eight patients were included in the study.

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Purpose: The implantation of an intraocular telescope increases life quality in patients with end-stage age-related macular degeneration (AMD). The present study monitored changes in electrophysiological markers of visual processing before and during seventeen months after a novel mirror telescope implantation in two patients (OV-male 90 years, MZ-female 70 years) with the final-stage form of AMD.

Methods: Visual evoked potentials were recorded to high-contrast pattern-reversal (PR-VEP for check size 40' and 10'), low-contrast motion-onset stimuli (in visual periphery M-VEP M20°, and in central part M-VEP C8°), and event-related potentials (ERPs) in the oddball visual paradigm.

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Purpose: To evaluate the success of a mini-invasive technique for operation of idiopathic macular hole (IMH).

Methods: We retrospectively examined 29 patients (30 eyes) in whom 25-G pars plana vitrectomy (PPV), peeling of the inner limiting membrane (ILM), and application of air tamponade were performed. The group of the patients included 7 males and 22 females (76%), age range 57-79 years (median 70).

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Article Synopsis
  • The study aimed to evaluate the occurrence of posterior capsule opacification (PCO) after cataract surgery using two different phacoemulsification methods: AquaLase and NeoSoniX, over an 8-year period.
  • It included a randomized trial with patients undergoing surgery on both eyes, using AquaLase on one eye and NeoSoniX on the other, with follow-up assessments at 1, 3, and 8 years post-surgery.
  • Results showed minimal differences in PCO levels between the two methods, indicating that neither technique significantly prevented the progression of PCO over time.
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Purpose: To prospectively compare the degree of posterior capsule opacification (PCO) after AquaLase and NeoSoniX phacoemulsification methods during the 3-year follow-up period.

Design: Prospective, randomized clinical trial.

Methods: Setting at the Department of Ophthalmology, University Hospital in Hradec Králové.

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Aims: To compare the metrics and surgical outcome when using Infiniti AquaLase and NeoSoniX cataract removal modalities.

Methods: This prospective clinical study involved 50 patients with bilateral cataracts and lens removal using AquaLase in the right eye and NeoSoniX in the left eye. Best corrected visual acuity (BCVA), endothelial cell density and pachymetry were evaluted pre- and postoperatively.

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Purpose: To compare the extent of corneal endothelial cell loss and pachymetry changes in 2 age-based groups of patients who had cataract removal by AquaLase (Alcon) phacoemulsification in 1 eye and NeoSoniX (Alcon) phacoemulsification in the contralateral eye.

Setting: Department of Ophthalmology, University Hospital, Hradec Králové, Czech Republic.

Methods: This prospective clinical study comprised 28 patients younger than 80 years (Group A) and 28 patients 80 years or older (Group B) with bilateral cataract having lens removal using AquaLase in the right eye and NeoSoniX in the left eye.

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Purpose: To compare the extent of posterior capsule opacification (PCO) after AquaLase and NeoSoniX phacoemulsification methods using two types of software for PCO quantification.

Design: Prospective, randomized clinical trial.

Methods: At the Department of Ophthalmology, University Hospital in Hradec Králové, 50 patients (100 eyes) were analyzed one year after surgery.

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