Synopsis of recent research by authors named "Jana Melegova"
- Jana Melegova's recent research includes developing a new in vitro model for Duchenne muscular dystrophy by creating an induced pluripotent stem cell line from pediatric blood samples, demonstrating its potential for further study of the disease.
- Her work emphasizes the differentiation capabilities of the derived iPS cells into three germ layers, validating the stem cell line's application in disease modeling and therapeutic research.
- Additionally, Melegova investigates the impact of voltage-gated sodium channel inhibitors on cough mechanisms in a guinea pig model, addressing the clinical need for effective treatments for excessive cough due to airway neural pathway dysregulation.
