MRI in lung transplant recipients using hyperpolarized 3He: comparison with CT.

Purpose: To elucidate the ability of 3He-MRI to detect ventilation defects in lung transplant recipients, 3He-MRI was compared to CT for concordance.

Materials And Methods: We examined 14 lung recipients using 3He-MRI on a 1.5 T MR scanner.

Dynamic ventilation (3)He-magnetic resonance imaging with lung motion correction: gas flow distribution analysis.

Rationale And Objectives: Software was developed to correct for lung motion to improve the description of hyperpolarized (3)He gas distribution in the lung.

Methods: Five volunteers were studied by dynamic ventilation (3)He-MRI using an ultrafast FLASH 2D sequence with a temporal resolution of 128 milliseconds. Signal kinetics were evaluated in the trachea and seven parenchymal Regions of Interest.