Importance of psychiatric examination in predictive genetic testing for Huntington disease.

Background And Purpose: Huntington disease (HD) is an au-tosomal dominant hereditary neurodegenerative disease with multiplication of CAG triplet in the short arm of chromoso-me 4, manifested by motor symptoms, cognitive dysfunction progressing to dementia, and various types of neuropsychiat-ric disorders. The diagnosis of HD is confirmed by a gene-tic test, which may also be carried out presymptomatically.

Material And Methods: We studied differences in psychiatric examination and psychometric measures among the 52 people at risk of HD, who were recommended to postpone or to continue in the predictive protocol.

Quality of life 1 year after aneurysmal subarachnoid hemorrhage in good outcome patients treated by clipping or coiling.

Background And Purpose: A study was conducted to compare the quality of life (QOL) of surgically versus endovascularly treated patients with ruptured cerebral aneurysms.

Methods: We treated 45 patients surgically (surgical clipping [SC] group) and 44 by endovascular therapy (coil embolization [CE] group). A standardized test of QOL and a structured interview were employed to assess changes 1 year after subarachnoid hemorrhage (SAH).

Smokers with intracranial aneurysms who underwent neurosurgical or endovascular treatment have not stopped smoking one year after surgery.

Smoking increases the risk of forming, growing, and rupture of intracranial aneurysms. We retrospectively reviewed patients with intracranial aneurysms treated by neurosurgical or endovascular treatment--154 patients (45 men, 109 women, 15 to 62 years, average 46.3 years, CI +/- 1.

Cognitive functions before and 1 year after surgical and endovascular treatment in patients with unruptured intracranial aneurysms.

Background And Purpose: This prospective study investigated whether surgery or endovascular treatment for unruptured intracranial aneurysms (UIAs) affects cognitive functions.

Methods: Four neuropsychological variables from an Auditory Verbal Learning Test (overall capacity of verbal memory and delayed recall) and a Trail Making Test (psychomotor speed and cognitive flexibility) were investigated before and 1 year after treatment for UIAs in 65 patients < 61 years of age. This cohort consists of 15 men and 50 women aged 15-60 (mean age 44.

Verbal memory capacity after treatment for ruptured intracranial aneurysm--the outcomes of three psychological tests: within a month, 1 year after and 5-7 years after treatment.

Background: Verbal memory is an essential cognitive ability with scope for adequate treatment of information and for orientation in everyday life. Our study is centered on memory performance in the wake of treatment for ruptured intracranial aneurysm.

Methods: Three psychological tests were performed: (1) within a month of the neurosurgical intervention, (2) 1 year and (3) 5-7 years after the ruptured aneurysm treatment.