Efficacy and Safety of Perioperative Use of Epinephrine for Laparoscopic Myomectomy in Infertile Women with Symptomatic Solitary Intramural Uterine Fibroids A Randomized Clinical Trial.

Objective: To determine the efficacy and safety of intramyometrial application of epinephrine during a laparoscopic myomectomy in women of reproductive age desiring pregnancy and with clinically symptomatic uter- ine fibroids, in comparison with a placebo-based patient control group.

Study Design: The study group (n=96, 53.3%) underwent an application of 12 μg epinephrine hydro- chloride diluted in 20 mL of NaCl solution, while the control group (n=84, 46.