Publications by authors named "Jana Juergensen"
Article Synopsis
- - The study focuses on zebrafish, where cilia in the Kupffer's vesicle create fluid flow that is crucial for proper left-right patterning in organ development; defects can lead to serious congenital issues.
- - The researchers discovered that the miR-103/107 microRNA family is important for regulating this left-right patterning; depletion of these microRNAs in zebrafish embryos resulted in heart and organ malformations.
- - The study also found that miR-103/107 influences cilia formation and KV development, with similar effects observed in human cells, highlighting a conserved role across species in regulating organ asymmetry.