Publications by authors named "Jana Diercks"
Article Synopsis
- Research identified substituted arylsulfoanilides as potential antiproliferative agents, showing effectiveness against lung cancer cells through intracellular Ca(2+) store depletion.
- The study found that certain substitution patterns on the arylsulfoanilides boosted their activity, leading to the creation of a hybrid compound, 27, combining arylsulfoanilide and 3-phenyloxindole.
- Compound 27 functions by inhibiting cancer cell growth through two mechanisms: reducing intracellular Ca(2+) stores and phosphorylating eIF2alpha.
