Publications by authors named "Jana Christina Hey"

Background: Adequate knowledge and awareness regarding diseases are essential for appropriate, high-quality healthcare. Female Genital Schistosomiasis (FGS) is a non-sexually transmitted gynaecological disease that is caused by the presence of Schistosoma haematobium eggs in the female genital tract and the resulting immune response that causes tissue damage. It is estimated to affect 56 million women, mostly in sub-Saharan Africa (SSA), where healthcare workers (HCWs) have limited awareness and knowledge of FGS.

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Infection with Schistosoma haematobium causes urogenital disease associated with organ disfunction, bleeding, pain, and higher susceptibility to infections and cancer. Timely and accurate diagnosis is crucial for prompt and appropriate treatment as well as surveillance efforts, and the use of plasma biomarkers offers important advantages over parasitological examination of urine, including increased sensitivity and the possibility to use the same specimen for multiple investigations. The present study aims to evaluate the diagnostic performance of different plasma biomarkers in endemic populations from Burkina Faso, West Africa.

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Article Synopsis
  • The study aimed to estimate the prevalence of Strongyloides stercoralis infection in four districts of Madagascar, focusing on coastal versus highland areas, where data on strongyloidiasis is limited.
  • Serum and fecal samples were analyzed using real-time PCR and serology, revealing a significantly higher prevalence of infection in coastal districts (20.9% and 35.2%) compared to highland districts (5.6% and 6.1%).
  • The research found a strong association between strongyloidiasis and hookworm infection, which was also linked to factors like male gender and lower education levels, suggesting potential public health interventions are needed in the most affected areas.
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