Publications by authors named "Jana Bosiers"

Pleural hemangiopericytoma/solitary fibrous tumor (HPC/SFT) is a rare form of mesenchymal tumor arising from pericytes, which predominantly occurs intrathoracically. HPC/SFT can be suspected on imaging, but radiographic features are non-specific. Therefore, histological confirmation remains the gold standard.

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Therapy with immune checkpoint inhibitors (ICIs) has significantly improved the prognosis of metastatic melanoma but is also associated with various immune-related adverse events (AE), including pulmonary toxicity. Herein, we describe the case of a 60-year-old female with metastasized melanoma with BRAF mutation under combination immunotherapy with ipilimumab and nivolumab, who presented with a persistent, nonproductive cough for the last two months. Her CT-scan showed de novo bronchial inflammation and wall thickening in all lung fields.

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Article Synopsis
  • Using intraoperative radiotherapy with electrons (IOERT) during breast surgery helps doctors see the tumor better, protects the skin, and is easier for patients.
  • In a study with 763 women, the IOERT treatment led to a very high success rate of 98.4% in preventing cancer from coming back after 5 years.
  • While some patients had mild complications and others showed changes in mammograms, the treatment was generally safe and effective overall.
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