Publications by authors named "Jan Trupl"

Geographic differences in frequency and azole resistance among Candida glabrata may impact empiric antifungal therapy choice. We examined geographic variation in isolation and azole susceptibility of C. glabrata.

View Article and Find Full Text PDF
Article Synopsis
  • The study analyzed 65 cases of Escherichia coli bacteremia over seven years in a cancer hospital, focusing on risk factors, patient outcomes, and antibiotic susceptibility.
  • It found that E. coli was responsible for 20.8% of Gram-negative bacteremia, with a notable mortality rate of 17%, and identified major risk factors like solid tumors, prior surgeries, and recent chemotherapy.
  • The research indicated that monomicrobial E. coli bacteremia led to lower mortality rates compared to polymicrobial cases, while most E. coli strains remained susceptible to various antibiotics with minimal resistance observed during the study period.
View Article and Find Full Text PDF

Among 1,011 recently isolated Streptococcus pyogenes isolates from 10 Central and Eastern European centers, the MICs at which 50% of isolates are inhibited (MIC(50)s) and the MIC(90)s were as follows: for telithromycin, 0.03 and 0.06 microg/ml, respectively; for erythromycin, azithromycin, and clarithromycin, 0.

View Article and Find Full Text PDF

The macrolide and levofloxacin susceptibilities of 992 isolates of Streptococcus pneumoniae from clinical specimens collected in 1999 and 2000 were determined in 10 centers in Central and Eastern European countries. The prevalences of penicillin G-intermediate (MICs, 0.125 to 1 microg/ml) and penicillin-resistant (MICs, < or =2 microg/ml) Streptococcus pneumoniae isolates were 14.

View Article and Find Full Text PDF

The aim of this study was to retrospectively compare the incidence, risk factors, and outcome in patients seen over a 7-year period at the National Cancer Institute in the Slovak Republic, with vancomycin-sensitive or vancomycin-resistant enterococcal bacteremia. The total incidence of enterococcal bacteremia at the National Cancer Institute increased from 5.1% in 1991 to 11.

View Article and Find Full Text PDF