Publications by authors named "Jan Toman"

The gradual decrease in the prevalence of serious infectious diseases over the last century has been followed by increase in so called "modern" diseases, including allergies, chronic inflammatory conditions, psychiatric, and metabolic disorders. Between 2019 and 2022, public awareness of the threat of infectious diseases in humans was renewed by the global pandemic of a new type of a coronavirus, the SARS-COV-2. This public interest opened improved possibilities to test hypotheses on the factors associated with inter-individual variation in susceptibility to infectious and "modern" diseases.

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Bacteria Borrelia burgdorferi s. l. and even more the protist Toxoplasma gondii Nicolle et Manceaux, 1908, are known to affect the behaviour and mental health of their animal and human hosts.

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Maintenance of genetic polymorphism remains one of the big questions of evolutionary biology, which for a long time tended to be explained by balancing selection. This explanation was later criticized, but now is again accepted as an important mechanism in evolution. Human blood group systems seem affected by balancing selection especially strongly.

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Article Synopsis
  • Previous research indicates that RhD positive heterozygotes experience better health outcomes compared to RhD positive homozygotes and RhD negative individuals, particularly in pregnant women.
  • The study aimed to evaluate whether RhD positive heterozygous mothers tend to have more male offspring, testing this using a cross-sectional analysis of data from over 5,600 women who gave birth between 2008 and 2012 in Prague.
  • Results showed a significantly higher male-to-female birth ratio in RhD positive mothers with RhD negative newborns (1.23) compared to those with RhD positive newborns (1.00), especially among first-time mothers.*
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Ecological theories of sexual reproduction assume that sexuality is advantageous in certain conditions, for example, in biotically or abiotically more heterogeneous environments. Such theories thus could be tested by comparative studies. However, the published results of these studies are rather unconvincing.

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Natural selection is considered to be the main process that drives biological evolution. It requires selected entities to originate dependent upon one another by the means of reproduction or copying, and for the progeny to inherit the qualities of their ancestors. However, natural selection is a manifestation of a more general persistence principle, whose temporal consequences we propose to name "stability-based sorting" (SBS).

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