Publications by authors named "Jan Stankiewicz"
Article Synopsis
- The study aimed to evaluate the quality of life (QoL) in patients with amyotrophic lateral sclerosis (ALS) using a shortened assessment scale (ALSAQ-5) and understand its relationship with factors like age, sex, and disease duration.
- A total of 44 ALS patients participated, and their QoL was measured using both the ALSAQ-40 and ALSAQ-5 scales, where a higher score indicated worse QoL.
- Results indicated that limitations in mobility, daily living, communication, and emotional health significantly impacted QoL, while eating and drinking challenges were less influential; the ALSAQ-5 proved to be a reliable tool for assessing QoL in clinical settings.
Introduction: Chemodectomas are relatively frequent tumors of the head and neck but their diagnosis in consideration of the slow growth is difficult. The aim of this study is pointing out of the attention on: (1) non-typical beginning of ill and diagnostic difficulties leading to delaying of putting the proper diagnosis, (2) symptoms which are cause of notifying the patient to the doctors of different specializations e.g.
View Article and Find Full Text PDFIntroduction: The cephalic zoster is a cranial neuritis, with great tendency to diffusion along the nerves. The objective of this article is both to report a case of cranial polineuritis due to herpes zoster infection with laryngeal involvement and review of the relevant literature.
Material And Methods: The case of 57-years-old man with unilateral laryngeal mucosal eruptions and complete left vocal paralysis is reported.
Unlabelled: Multiple symmetric lipomatosis (MSL) is a systemic disease connected with a degeneration of the adipose tissue. Association of reduced glucose tolerance, hyperinsulinemia, hyperlipoproteinemia, hyperuricemia, macrocytic anemia and renal tubular acidosis, polyneuropathy have been described. Lipomatosis was initially described in 1846 by Brodie but the exact aetiopathogenesis is still unknown.
View Article and Find Full Text PDFRecent reports have proved that genetic factors play a role in the pathogenesis of sporadic Parkinson's disease (PD). It has been suggested that polymorphisms in monoamine oxidase B (MAOB) and catechol-O-methyltransferase (COMT) might increase the risk of PD. A total of 210 Polish patients with sporadic PD and 152 healthy controls were studied.
View Article and Find Full Text PDFThe aim of the study was to determine the prevalence of primary dystonia in Szczecin Region (total population of 995,000 individuals) and Gdansk Region (total population of 149,000 individuals). We identified on the prevalence day 31.12.
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- * A case of sporadic CJD lasting 12 months was reported, which was confirmed through the presence of 14-3-3 protein in the patient's tests.
- * This particular case showed significant neuron loss in many grey matter areas of the brain, indicating a severe progression of the disease.
P-glycoprotein is a membrane protein encoded by the MDR1 gene, which demonstrates functional polymorphism. It is present in endothelial cells of the blood-brain barrier, thus limiting accumulation of its substrates in the central nervous system. Many epidemiological studies suggest an association between pesticides, which are substrates for P-glycoprotein, and Parkinson's disease.
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- - The study investigated the role of N-acetyltransferase 2 polymorphism in Polish patients with Parkinson's disease, highlighting its potential genetic influence on the disease's development.
- - Researchers compared 54 Parkinson's patients to 81 healthy individuals and found that a higher percentage of patients were slow acetylators, with 64.8% having mutations linked to this phenotype, while the control group had more fast acetylators.
- - The results suggest that being a slow acetylator significantly increases the risk of developing Parkinson's disease, indicating this genotype may contribute to individual susceptibility to the condition.