Publications by authors named "Jan Schenkel"

In order to be able to perform major oral surgery in the upper jaw, sufficient local analgesia is indispensable. While the inferior alveolar nerve is often blocked for dental treatments in the lower jaw, block anesthesia in the upper jaw is less common. This article gives pragmatic advice on how to block the infraorbital nerve.

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Patients with solid organ transplants can be challenge to manage pre- and postoperatively. Dental care should be given to these patients prior to surgery in order to achieve healthy oral conditions. Periodontitis has to be treated, in- sufficient root canal treatments need to be revised, cavities shall be filled and teeth that cannot be salvaged should be extracted.

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Patients with solid organ transplants can be a challenge to manage pre- and postoperatively. Dental care should be given to these patients prior to surgery in order to achieve healthy oral conditions. Periodontitis has to be treated, insufficient root canal treatments need to be revised, cavities shall be filled and teeth that cannot be salvaged should be extracted.

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This script gives a pragmatic advice for gen-eral dentists on accurate use of amoxicillin with clavulanic acid considering current liter-ature at acute inflammatory disease. In ab-sence of contraindications a twice daily for- mulation of 1g amoxicillin with clavulanic acid is the first choice for concomitant therapy after treating the cause of inflammation or prophy-laxis. Compared to clindamycin the concen-tration of amoxicillin in teeth and bone (Hallig 2014) is higher and has less gastrointestinal side-effects (Bax 2007).

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This script gives a pragmatic advice for general dentists on accurate use of amoxicillin with clavulanic acid considering current literature at acute inflammatory disease. In absence of contraindications a twice daily formulation of 1g amoxicillin with clavulanic acid is the first choice for concomitant therapy after treating the cause of inflammation or prophylaxis. Compared to clindamycin the concentration of amoxicillin in teeth and bone (Hallig 2014) is higher and has less gastrointestinal side-effects (Bax 2007).

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Oral lichen planus is a relatively common T-cell mediated inflammatory disease with potential malignant transformation. It may present itself with pain and oral lesions such as ulcers and Wickham’s striae. Treatment includes topical corticosteroids, preferably Clobetasol, immunosuppressive drugs and retinoids.

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Reliable analgesia can nowadays be achieved with several techniques and different anesthetic solutions, but side effects may be encountered. Severe and potentially fatal cardiovascular reactions can be the result of an intravascular injection. An easy to use, effective and safe alternative is the periodontal ligament injection.

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Purpose: The long-term survival benefit of neoadjuvant radiotherapy for oropharyngeal tumors is controversially discussed in the literature. To bring more light into this important debate, we evaluated our cases.

Patients And Methods: In this retrospective study the main focus was the relationship between neoadjuvant irradiation and anastomosis failure.

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Purpose: Mandibular fractures are amongst the most common facial fractures and are usually treated by open reduction and internal fixation (ORIF). Inferior alveolar nerve (IAN) injuries are seen frequently in mandibular fractures as well as after ORIF of these fractures due to the exposition and the close proximity of the nerve during fracture reduction. Therefore the continuity of the IAN can be disrupted.

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Local anaesthetics are an integral part of most dental procedures and are therefore widely used and safely applied. Though rare, complications may occur and can be categorized as local or systemic. In the majority they are of minor nature but there is a potential for severe and possibly lethal side effects.

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In dentomaxillofacial radiology, cone-beam computed tomography (CT) is used to give fast and high-resolution 3-dimensional images of bone with a low dose of radiation. However, its use for quantitative measurement of bone density based on absolute values (Hounsfield units, HU) as in multidetector CT is still controversial. We know of no in vivo study of 3-dimensional merging software that will reliably match identical bone areas of cone-beam and multidetector CT datasets.

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Local anaesthetics are an integral part of most dental procedures and are therefore widely used and safely applied. Though rare, complications may occur and can be categorized as local or systemic. In the majority they are of minor nature but there is a potential for severe and possibly lethal side effects.

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Oral lichen planus is a relatively common T-cell mediated inflammatory disease with potential malignant transformation. It may present itself with pain and oral lesions such as ulcers and Wickham's striae. Treatment includes topical corticosteroids, preferably Clobetasol, immunosuppressive drugs and retinoids.

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Article Synopsis
  • The study evaluates the effectiveness of treating comminuted mandibular fractures using an intraoral approach for open reduction and internal fixation, highlighting a shift from traditional methods.
  • Data collected from 45 patients at Zurich University Hospital showed that 84% had excellent postoperative results, with complications in 16% including wound dehiscence and osteomyelitis.
  • The intraoral approach is suggested to be equally effective as the extraoral method, with lower risks of nerve damage and visible scarring, though the best technique should be chosen case-by-case.
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Dual-responsive soft matter: A soft hybrid material composed of superparamagnetic nanoparticles and cyclodextrin vesicles self-assembles in microscale linear aggregates in water in response to magnetic field as well as light.

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Article Synopsis
  • Researchers studied how proteins can be assembled on surfaces using a technique that incorporates specific supramolecular groups into them.
  • They used a labeling method called SNAP-tag to attach ferrocenes to fluorescent proteins, creating stable monolayers on specialized surfaces coated with cyclodextrin and cucurbit[7]uril.
  • The findings show that this method allows for precise assembly and visualization of modified proteins, expanding options for creating intricate protein patterns on various surfaces.
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Objective: The University Hospital of Zurich provides a medical online consultation service since 1999. Our aim was to characterise the users of an online consultation with queries regarding maxillofacial surgery, to analyse the content of their questions and to study the actions by the internet doctors with the ambition of defining whether the telemedical consultation is a useful tool in this surgical field.

Materials And Methods: The procedure of inductive category development described by MAYRING was used.

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Supramolecular assembly of proteins on surfaces and vesicles was investigated by site-selective incorporation of a supramolecular guest element on proteins. Fluorescent proteins were site-selectively labeled with bisadamantane by SNAP-tag technology. The assembly of the bisadamantane functionalized SNAP-fusion proteins on cyclodextrin-coated surfaces yielded stable monolayers.

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