Publications by authors named "Jan Sag Schouten"

Purpose: The aim of this study is to generate reference values for anterior chamber morphometrics to facilitate the interpretation of anterior chamber images acquired with swept-source optical coherence tomography (SS-OCT) in a Caucasian population.

Materials And Methods: Non-glaucomatous Caucasian subjects, who were newly referred to the outpatient department of the University Eye Clinic Maastricht UMC+, were asked to undergo anterior segment assessment with SS-OCT imaging prior to routine eye examination (including visual acuity and refractive error measurements, Goldmann applanation tonometry, slit lamp examination and funduscopy).

Results: A total of 647 Caucasian subjects, aged 40-80 years, were included.

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Article Synopsis
  • * Comprehensive eye examinations and next-generation sequencing (NGS) identified specific mutations in the CHM gene, which were confirmed in both families, with asymptomatic family members identified as carriers.
  • * The findings highlight how these genetic mutations impact retinal health, leading to abnormalities due to diminished production of Rab escort protein-1 (REP-1), which is crucial for retinal function.
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Objective: To study visual complaints and eye diseases among professional and amateur orchestral musicians in the Netherlands.

Methods: In this observational study, members from professional and amateur symphony or wind orchestras were asked to complete a questionnaire collecting demographic data, musical, medical, and family history, and data on present visual complaints and/or eye diseases. Questions about playing in the orchestra were also asked.

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Brinzolamide 1%/timolol 0.5% is a new fixed-combination for the treatment of open-angle glaucoma or ocular hypertension. Brinzolamide/timolol has a favorable safety profile, with an incidence of ocular burning and stinging <5%.

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