Publications by authors named "Jan Robak"
Article Synopsis
- Dilated cardiomyopathy (DCM) often results in left ventricle dilation and systolic dysfunction, with evidence suggesting a significant presence of left ventricular diastolic dysfunction (LVDD) in these patients.
- The study involved 102 DCM patients who were assessed for cardiac fibrosis through late gadolinium enhancement and extracellular volume measurements, categorizing them based on left atrial pressure levels.
- Findings revealed that 42% of patients had elevated left atrial pressure, with larger extracellular volumes indicating more severe LVDD, making extracellular volume a key independent predictor of LVDD in DCM patients.
Background: By definition, dilated cardiomyopathy (DCM) is characterized by enlargement of the left ventricular (LV) cavity, and systolic dysfunction. However, in 2016 ESC introduced a new clinical entity - hypokinetic non-dilated cardiomyopathy (HNDC). HNDC is defined as LV systolic dysfunction without LV dilatation.
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- Dilated cardiomyopathy (DCM) is a leading cause of heart failure with a 20% mortality rate in 5 years, yet there's a lack of validated risk assessment tools for these patients.
- A study of 735 DCM patients calculated their mortality risk using the Krakow DCM Risk Score and followed them for about 42 months.
- The results showed that the Krakow DCM Risk Score effectively identified high-risk patients, with those having a >6% 2-year mortality risk experiencing significantly higher death rates compared to lower-risk patients.
The relationship between circulating fibrosis-related molecules and magnetic resonance-assessed cardiac fibrosis in dilated cardiomyopathy (DCM) is poorly understood. To compare circulating biomarkers between DCM patients with high and low fibrosis burdens, we performed a prospective, single-center, observational study. The study population was composed of 100 DCM patients (87 male, mean age 45.
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