Publications by authors named "Jan Paczesny"

Bacteriophage infections in bacterial cultures pose a significant challenge to industrial bioprocesses, necessitating the development of innovative antiphage solutions. This study explores the antiphage potential of indigo carmine (IC), a common FDA-approved food additive. IC demonstrated selective inactivation of DNA phages (P001, T4, T1, T7, λ) with the EC values ranging from 0.

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Article Synopsis
  • Cutting-edge research is focusing on creating multifunctional nanomaterials for high-tech uses, specifically using a solvent-free solid-state method to develop quantum dot hydroxyapatite (HA) from bovine bone waste.
  • The incorporation of cobalt and magnesium into the HA structure enhances crystallinity and shifts the material's bandgap to the visible light range, allowing it to respond to light.
  • The resulting Co/Mg co-doped HA nanoparticles exhibit magnetization, biocompatibility, and strong antimicrobial effects against harmful bacteria, indicating their potential for sustainable biomedical applications in anti-infection treatments.
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The impact of the reaction environment on the formation of the polycrystalline layer and its biomedical (antimicrobial) applications were analyzed in detail. Copper oxide layers were synthesized using an electrodeposition technique, with varying additives influencing the morphology, thickness, and chemical composition. Scanning electron microscopy (SEM) images confirmed the successful formation of polyhedral structures.

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Humans have used fermentation processes since the Neolithic period, mainly to produce beverages. The turning point occurred in the 1850s, when Louis Pasteur discovered that fermentation resulted from the metabolism of living microorganisms. This discovery led to the fast development of fermented food production.

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The sale of antibiotics and antifungals has skyrocketed since 2020. The increasing threat of pathogens like ESKAPE bacteria (, , , , , and spp.), which are effective in evading existing antibiotics, and yeasts like or is pressing to develop efficient antimicrobial alternatives.

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Article Synopsis
  • - The research focuses on developing adaptive Langmuir films that can change in response to environmental stimuli, specifically studying the behavior of nanoparticles capped with a poly(-isopropyl acrylamide) layer.
  • - By varying temperatures, the study shows that these nanoparticles can switch between densely packed uniform states and nonuniform states, suggesting an unusual phase behavior where order increases with higher temperatures.
  • - The findings help inform the design of advanced two-dimensional systems, like programmable membranes and optical devices, through various experimental techniques like surface pressure measurements and microscopy.
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Two-dimensional and pseudo-2D systems come in various forms. Membranes separating protocells from the environment were necessary for life to occur. Later, compartmentalization allowed for the development of more complex cellular structures.

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The objective of this study is to explore the effects of microplastics on the viability of the bacteriophages in an aqueous environment. Bacteriophages (phages), that is, viruses of bacteria, are essential in homeostasis. It is estimated that phages cause up to 40% of the death of all bacteria daily.

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Bacteriophages are viruses that infect bacteria and thus threaten industrial processes relying on the production executed by bacterial cells. Industries bear huge economic losses due to such recurring and resilient infections. Depending on the specificity of the process, there is a need for appropriate methods of bacteriophage inactivation, with an emphasis on being inexpensive and high efficiency.

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The study's main objective is to limit bacterial biofilm formation on fixed orthodontic appliances. Bacterial biofilm formation on such devices (e.g.

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The presented research shows the possibilities of creating in-line magnetic sensors based on the detection of changes of light propagation parameters, especially polarization, obtained by mixing FeO nanoparticles with hexadecane (higher alkane) surrounding a biconical optical fiber taper. The fiber optic taper allows to directly influence light parameters inside the taper without the necessity to lead the beam out of the structure. The mixture of hexadecane and FeO nanoparticles forms a special cladding surrounding a fiber taper which can be controlled by external factors such as the magnetic field.

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Phages are efficient in diagnosing, treating, and preventing various diseases, and as sensing elements in biosensors. Phage display alone has gained attention over the past decade, especially in pharmaceuticals. Bacteriophages have also found importance in research aiming to fight viruses and in the consequent formulation of antiviral agents and vaccines.

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Bacteriophages are viruses that attack and usually kill bacteria. Their appearance in the industrial facilities using bacteria to produce active compounds (e.g.

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We analyze a compressible Poiseuille flow of ideal gas in a plane channel. We provide the form of internal energy U for a nonequilibrium stationary state that includes viscous dissipation and pressure work. We demonstrate that U depends strongly on the ratio Δp/p_{0}, where Δp is the pressure difference between inlet and outlet and p_{0} is the outlet's pressure.

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Article Synopsis
  • Viral infections from bacteriophages pose a serious threat to bacteria in bioreactors, affecting over 70% of biotechnology companies without reliable prevention methods.
  • A new technology using gold nanoparticles coated with specific ligands has been developed to effectively deactivate various bacteriophages while remaining safe for beneficial bacteria.
  • The nanoparticles significantly reduce phage levels in a matter of hours and work well in conditions similar to those found in bioreactors, showcasing their potential for protecting bacterial processes in biotechnology.
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Bacteriophages (phages) are a specific type of viruses that infect bacteria. Because of growing antibiotic resistance among bacterial strains, phage-based therapies are becoming more and more attractive. The critical problem is the storage of bacteriophages.

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Hypothesis: The type and properties of ligands capping nanoparticles affect the characteristics of corresponding Langmuir and Langmuir-Blodgett films. When ligands are firmly anchored to the surface, as in zinc oxide nanocrystallites (ZnO NCs), compression at the air/water interface might cause ligands interdigitation and then the formation of supra-structures. Here, we evaluate how the introduction of bulky ligands, namely polyhedral oligomeric silsesquioxanes (POSSs), influences the self-assembly of POSS@ZnO NCs and the properties of corresponding thin films.

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Antimicrobial resistance is a significant threat to human health worldwide, forcing scientists to explore non-traditional antibacterial agents to support rapid interventions and combat the emergence and spread of drug resistant bacteria. Many new antibiotic-free approaches are being developed while the old ones are being revised, resulting in creating unique solutions that arise at the interface of physics, nanotechnology, and microbiology. Specifically, physical factors (e.

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Hydrophobicity is one of the most critical factors governing the adsorption of molecules and objects, such as virions, on surfaces. Even moderate change of wetting angle of plastic surfaces causes a drastic decrease ranging from 2 to 5 logs of the viruses (e.g.

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Bacteriophages (phages for short) are viruses, which have bacteria as hosts. The single phage body virion, is a colloidal particle, often possessing a dipole moment. As such, phages were used as perfectly monodisperse systems to study various physicochemical phenomena (e.

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Two oppositely charged surfaces separated by a dielectric medium attract each other. In contrast we observe a strong repulsion between two plates of a capacitor that is filled with an aqueous electrolyte upon application of an alternating potential difference between the plates. This long-range force increases with the ratio of diffusion coefficients of the ions in the medium and reaches a steady state after a few minutes, which is much larger than the millisecond timescale of diffusion across the narrow gap.

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Bacteria will likely become our most significant enemies of the 21st century, as we are approaching a post-antibiotic era. Bacteriophages, viruses that infect bacteria, allow us to fight infections caused by drug-resistant bacteria and create specific, cheap, and stable sensors for bacteria detection. Here, we summarize the recent developments in the field of phage-based methods for bacteria detection.

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The majority of analytical chemistry methods requires presence of target molecules directly at a sensing surface. Diffusion of analyte from the bulk towards the sensing layer is random and might be extremely lengthy, especially in case of low concentration of molecules to be detected. Thus, even the most sensitive transducer and the most selective sensing layer are limited by the efficiency of deposition of molecules on sensing surfaces.

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When components of a metal-organic framework (MOF) and a crystal growth modulator diffuse through a gel medium, they can form arrays of regularly-spaced precipitation bands containing MOF crystals of different morphologies. With time, slow variations in the local concentrations of the growth modulator cause the crystals to change their shapes, ultimately resulting in unusual concave microcrystallites not available via solution-based methods. The reaction-diffusion and periodic precipitation phenomena 1) extend to various types of MOFs and also MOPs (metal-organic polyhedra), and 2) can be multiplexed to realize within one gel multiple growth conditions, in effect leading to various crystalline phases or polycrystalline formations.

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Evolution of bacteria to selective chemical pressure (e.g. antibiotics) is well studied in contrast to the influence of physical stressors.

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