Systematic Literature Review of Spinal Cord Stimulation in Patients With Chronic Back Pain Without Prior Spine Surgery.

Objective: Low back pain is the leading cause of disability worldwide and one of the most common reasons for seeking healthcare. Despite numerous care strategies, patients with low back pain continue to exhibit poor outcomes. Spinal cord stimulation (SCS) is an evidence-based therapeutic modality for patients with failed back surgery syndrome.

Intramedullary spinal cord metastasis from prostate carcinoma: a case report.

Introduction: Although vertebral and epidural metastases are common, intradural metastases and intramedullary spinal cord metastases are rare. The indications for the treatment of intramedullary spinal cord metastases remain controversial. We present the first biopsy-proven case of an intramedullary spinal cord metastasis from adenocarcinoma of the prostate.

Potential application of hydrogen in traumatic and surgical brain injury, stroke and neonatal hypoxia-ischemia.

This article summarized findings of current preclinical studies that implemented hydrogen administration, either in the gas or liquid form, as treatment application for neurological disorders including traumatic brain injury (TBI), surgically induced brain injury (SBI), stroke, and neonatal hypoxic-ischemic brain insult (HI). Most reviewed studies demonstrated neuroprotective effects of hydrogen administration. Even though anti-oxidative potentials have been reported in several studies, further neuroprotective mechanisms of hydrogen therapy remain to be elucidated.

Hydrogen is neuroprotective against surgically induced brain injury.

Background: Neurosurgical operations cause unavoidable damage to healthy brain tissues. Direct surgical injury as well as surgically induced oxidative stress contributes to the subsequent formation of brain edema. Therefore, we tested the neuroprotective effects of hydrogen (H2) in an established surgical brain injury (SBI) model in rats.

Ten-year clinical epidemiological trends of intracerebral hemorrhage in Chongqing, China.

Background: The combination of an increase in aged population and adaptation of Western lifestyle is modifying the epidemiological status of intracerebral hemorrhage in China. The purpose of this study is to analyse and characterize the changing trends of intracerebral hemorrhage in Chongqing, the largest city in Southwest China, over the past 10 years.

Methods: We retrospectively reviewed the medical records of patients diagnosed with intracerebral hemorrhage who visited the First Affiliated Hospital of Chongqing Medical University from 1 January 1998 to 31 December 1998 and from 1 January 2008 to 31 December 2008, respectively.

Arterial thrombosis and gangrene secondary to arachnidism.

Spider bites can cause local tissue damage as well as life-threatening complications. This is a case report of a female with no history of lower extremity vascular disease who presented with a spider bite on the dorsum of her foot. She developed progressive necrosis and eventually suffered limb loss despite attempts at revascularization.

Initial investigation of the potential of modified porcine erythrocytes for transfusion in primates.

There is a shortage of human blood for transfusion. The possibility of using alpha-galactosidase-treated pig red blood cells (pRBCs) for transfusion into humans has been investigated. pRBCs were treated in vitro with alpha-galactosidase.