GJB2 gene mutations in cochlear implant recipients: prevalence and impact on outcome.

Objective: To determine the prevalence of GJB2 gene mutations in patients undergoing cochlear implantation (CI) and their impact on rehabilitative outcome following implantation.

Design: Prospective determination of GJB2 mutation by sequence analysis by denaturing high-performance liquid chromatography and its correlation with outcome following CI.

Settings: Two tertiary academic medical centers.