Publications by authors named "Jan Koziej"
Article Synopsis
- Two pediatric patients with Crohn's disease experienced kidney injury linked to ADM therapy; one showed irreversible damage despite treatment, while the other's kidney function improved after stopping the drug.
- Monitoring kidney function and consulting specialists are crucial for patients on ADM, as timely discontinuation can prevent further damage but may not reverse existing harm.
Background And Objecitves: The currently available kidney volume normative values in children are restricted to small populations from single-centre studies not assessing kidney function and including none or only a small number of adolescents. This study aimed to obtain ultrasound-based kidney volume normative values derived from a large European White/Caucasian paediatric population with normal kidney function.
Methods: After recruitment of 1427 children aged 0-19 years, 1396 individuals with no history of kidney disease and normal estimated glomerular filtration rate were selected for the sonographic evaluation of kidney volume.
Arterial hypertension (HT) is a main, potentially reversible cardiovascular risk factor. Long lasting HT leads to hypertension mediated organ damage (HMOD) of heart, vascular bed, and kidneys. Assessment of HMOD is a standard diagnostic procedure in hypertensive adults and presence of HMOD is associated with increased cardiovascular risk.
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