Purpose: Online optical coherence pachymetry (online OCP) allows continuous central corneal thickness measurements over time. In this study, the effect of dehydration on corneal tissue was investigated with online OCP.
Methods: Twelve eyes of 11 patients were examined with online OCP, and the central corneal thickness was registered over 5 minutes after insertion of an eyelid speculum.
The trabecular meshwork is considered a smooth muscle like tissue contributing to aqueous outflow regulation and thus to regulation of intraocular pressure. An elevation in intraocular pressure is one of the greatest risk factors for most forms of glaucoma. We assume that contraction of trabecular meshwork reduces aqueous humor outflow and thus enhances intraocular pressure, whereas relaxation exerts the opposite effect.
View Article and Find Full Text PDFGraefes Arch Clin Exp Ophthalmol
January 2004
Purpose: Online optical coherence pachymetry (OCP) allows to monitor central changes of the corneal cross section intraoperatively. In this experimental evaluation the validity of the optical measurements for corneal refractive surgery was assessed.
Methods: Online OCP based on low-coherence interferometry with a wavelength of 1310 nm and a measurement frequency of 74 Hz was directly integrated in a clinical excimer laser.
Invest Ophthalmol Vis Sci
September 2003
Purpose: To investigate the effect of FGF-2 on corneal endothelial cell survival in porcine and human corneas during corneal storage in a serum-free medium.
Methods: Porcine and paired human corneas were stored at 32 degrees C for 9 and 22 days, respectively. One cornea of each pair was stored in a serum-free culture medium, and the mate was preserved in the same medium supplemented with 10 ng/mL FGF-2.