Publications by authors named "Jan Jaap van der Net"
We report the clinical course of three patients with refractory juvenile dermatomyositis (JDM) who were treated with tacrolimus. All three children had extensive skin disease and severe muscle weakness and were corticosteroid dependent. All three patients showed impressive improvement of mainly the cutaneous lesions.
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- The study aimed to assess if vaccinations worsen autoimmune diseases like juvenile idiopathic arthritis (JIA) and if immunosuppressive therapy affects vaccination response.
- 234 JIA patients (ages 1-19) were vaccinated with the MenC vaccine and monitored for disease activity for one year, showing no worsening of disease symptoms or relapse rates post-vaccination.
- The results indicated that the MenC vaccine is safe for JIA patients, as it didn't worsen their condition and effectively triggered a strong immune response, even in those on immunosuppressive treatments.
Objectives: To study (1). changes in anthropometrics, joint range of motion (ROM), muscle strength, functional ability, caregiver assistance, and level of ambulation in children with osteogenesis imperfecta (OI) and (2). the prediction of clinical characteristics at the level of ambulation at follow-up and the prediction of clinical characteristics on progression or regression at the level of ambulation over time.
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