Structure-Property Relationships of Polyamide 12 Grades Exposed to Rapid Crack Extension.

Thermoplastic materials have established a reputation for long-term reliability in low-pressure gas and water distribution pipe systems. However, occasional (SCG) and (RCP) failures still occur. SCG may initiate only a small leak, but it has the potential to trigger RCP, which is much rarer but more catastrophic and destructive.

Two-dimensional pH mapping of release kinetics of silica-encapsulated drugs.

The encapsulation of pharmaceutical drug molecules in silica gels during the sol-gel synthesis and their kinetic release profile in aqueous solutions were systematically investigated in dependence of synthesis pH(S) and extraction pH(E) values. Six pH values in the range from 1 to 6 were chosen in a 6 × 6 two-dimensional matrix to screen the first-order initial dissolution rate constant and the total amount of released drug. Characteristic differences are discovered in such two-dimensional pH mapping profiles for the molecules with different ionization behavior and they are explained by surface imprinting and encapsulation processes.