Publications by authors named "Jan Forner"
Article Synopsis
- The study evaluates the impact of right bundle branch block (RBBB) and left bundle branch block (LBBB) on the prognosis of patients with cardiogenic shock (CS), focusing on 30-day mortality rates.
- It involved 248 adult patients from an ICU in Germany, finding that those with RBBB had the highest mortality at 72.5%, compared to 52.9% for LBBB and 50.0% for no block.
- RBBB significantly predicted increased mortality even after adjusting for key health indicators, while LBBB showed no significant association with mortality outcomes.
Aims: Data regarding the characterization and outcomes of patients with heart failure (HF) with mildly reduced ejection fraction (HFmrEF) is scarce. This study investigates the characteristics and prognostic impact of native aortic valve diseases (AVD) in patients with HFmrEF.
Methods And Results: Consecutive patients hospitalized with HFmrEF (i.
: The occurrence of ventricular tachyarrhythmias represents an established risk factor of mortality in heart failure (HF). However, data concerning their prognostic impact in heart failure with mildly reduced ejection fraction (HFmrEF) is limited. Therefore, the present study aims to investigate patient characteristics associated with ventricular tachyarrhythmias and their prognostic impact in patients with HFmrEF.
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- The study looked at how tricuspid regurgitation (TR), a heart problem, affects patients who are in cardiogenic shock (CS), which is a serious condition where the heart can't pump enough blood.
- Researchers checked medical records and used special tests to see how different levels of TR influenced how long patients survived after 30 days.
- They found that patients with severe TR had a higher chance of dying within 30 days compared to those with less severe TR, especially in patients without a heart attack.
Objective: The study investigates the prognostic impact of the severity and etiology of chronic kidney disease (CKD) in patients with heart failure with mildly reduced ejection fraction (HFmrEF).
Background: Data regarding the outcomes in patients with CKD in HFmrEF is scarce.
Methods: Consecutive patients with HFmrEF were retrospectively included at one institution from 2016 to 2022.
Article Synopsis
- The study examines how previous left ventricular ejection fraction (LVEF) affects prognosis in patients with mildly reduced ejection fraction (HFmrEF) heart failure, a condition often overlooked in terms of prognostic impact.
- It retrospectively analyzed 689 patients from 2016 to 2022, categorizing them into three groups based on changes in LVEF: stable, improved, and deteriorated.
- Results showed no significant differences in all-cause mortality or hospital readmissions among the groups at 12 and 30 months, indicating that changes in LVEF do not significantly influence patient outcomes in this population.
Background: Data regarding the characterization and outcomes of diabetics with heart failure with a mildly reduced ejection fraction (HFmrEF) is scarce. This study investigates the prevalence and prognostic impact of type 2 diabetes in patients with HFmrEF.
Methods: Consecutive patients with HFmrEF (i.
Introduction: The presence of acute kidney injury (AKI) was shown to increase the risk of mortality following acute myocardial infarction; however, data regarding the prognostic impact of early AKI in patients with concomitant cardiogenic shock (CS) is limited. The study investigates predictors and the prognostic impact of AKI in patients with CS.
Methods: Consecutive patients with CS from 2019 to 2021 were included at one institution.
Article Synopsis
- This study examines the effectiveness of NT-proBNP as a biomarker for diagnosing and predicting outcomes in patients with heart failure and mildly reduced ejection fraction (HFmrEF), focusing on their kidney function (eGFR).
- Among the 755 patients analyzed, those with acute decompensated heart failure (ADHF) showed significantly higher NT-proBNP levels compared to those without, indicating its potential as a diagnostic tool.
- Higher NT-proBNP levels (> 3946 pg/mL) were linked to increased rates of death over 30 months, but its predictive value was diminished in patients with severely reduced kidney function (eGFR < 30 mL/min).
This study investigates the prognostic impact of left ventricular ejection fraction (LVEF) and tricuspid annular plane systolic excursion (TAPSE) in patients with sepsis and septic shock. Consecutive patients with sepsis and septic shock were included from 2019 to 2021. LVEF and TAPSE were assessed during the first 24 hours of intensive care unit (ICU) treatment.
View Article and Find Full Text PDFWe aimed to investigate the safety, feasibility, and long-term results of drug-eluting stent implantation before covered stents for treating coronary artery perforation (CAP). Between 2015 and 2020, 12,733 patients undergoing percutaneous coronary intervention (PCI) were retrospectively analyzed. The primary endpoint was 1-year target lesion revascularization (TLR), whereas secondary endpoints included the rate of major adverse cardiac and cerebrovascular events (MACCE) and all-cause death at 1 year.
View Article and Find Full Text PDFPrognostic impact of acute decompensated heart failure in patients with heart failure with mildly reduced ejection fraction.
Eur Heart J Acute Cardiovasc Care
February 2024
Article Synopsis
- This study looked at how acute decompensated heart failure (ADHF) affects patients who have heart failure with mildly reduced ejection fraction (HFmrEF).
- Researchers found that patients with ADHF had a much higher chance of dying or being hospitalized again compared to those without ADHF.
- The conclusion is that having ADHF is common and makes health outcomes worse for patients with HFmrEF.
Background: The study investigates the prognostic impact of D-dimer levels in patients with cardiogenic shock (CS). Although D-dimer levels were found to be associated with prognosis in various clinical settings such as heart failure or acute myocardial infarction (AMI), the prognostic role of D-dimer levels in CS patients has not yet been clarified.
Methods: Consecutive CS patients with and without concomitant AMI were prospectively included from 2019 to 2021.
The study investigates the prognostic value of the platelet count in patients with cardiogenic shock (CS). Limited data regarding the prognostic value of platelets in patients suffering from CS is available. Consecutive patients with CS from 2019 to 2021 were included at one institution.
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- This study assesses the predictive value of the tricuspid annular plane systolic excursion (TAPSE) and its ratio to pulmonary artery systolic pressure (PASP) in patients experiencing cardiogenic shock (CS).
- The research involved analyzing 90 patients admitted for CS over a two-year period and found that both TAPSE and the TAPSE/PASP ratio could predict 30-day mortality, particularly with lower values indicating worse outcomes.
- However, while the TAPSE <18 mm was a significant predictor of 30-day all-cause mortality, the TAPSE/PASP ratio did not enhance mortality risk prediction when adjusted for other variables.
Article Synopsis
- * It involved 217 CS patients, revealing a high overall mortality rate of 56% within 30 days, with findings showing that higher cTNI levels were linked to increased mortality risk, while NT-proBNP did not demonstrate significant predictive value.
- * Statistical analyses indicated that cTNI could effectively differentiate between survivors and non-survivors (AUC = 0.669), confirming its importance as a prognostic biomarker for 30-day all
Clinical outcomes in patients with reduced left ventricular systolic function undergoing rotational atherectomy (RA) for percutaneous coronary intervention (PCI) remain understudied. Our study sought to evaluate the impact of RA-PCI in patients with LV systolic dysfunction on long-term outcomes. Between 2015 and 2019, 4941 patients with reduced LV function (rEF) undergoing PCI (with or without RA) were included in the hospital database.
View Article and Find Full Text PDFThis study investigates the prognostic value of the aspartate-to-alanine aminotransferase ratio (i.e., AST/ALT ratio) and bilirubin in patients with cardiogenic shock (CS).
View Article and Find Full Text PDFAtrial fibrillation (AF) is associated with increased risk of mortality in various clinical conditions. However, the prognostic role of preexisting and new-onset AF in critically ill patients, such as patients with septic or cardiogenic shock remains unclear. This study investigates the prognostic impact of preexisting and new-onset AF on 30-day all-cause mortality in patients with septic or cardiogenic shock.
View Article and Find Full Text PDFBackground: The spectrum of patients with cardiogenic shock (CS) has changed significantly over time. CS has become especially more common in the absence of acute myocardial infarction (AMI), while this subset of patients was typically excluded from recent studies. Furthermore the prognostic impact of onset time and onset place due to CS has rarely been investigated.
View Article and Find Full Text PDFBackground: Data regarding the short-term prognostic impact of hemoglobin levels in cardiogenic shock (CS) patients is limited. The study examines the prognostic impact of hemoglobin levels in patients with CS.
Methods: Consecutive patients with CS of any etiology from 2019 to 2021 were included at one institution.
Although previous studies investigated the influence of cardiovascular risk (CVR) factors in patients with acute coronary syndrome, data concerning the effect of CVR factors on the prognosis of patients with cardiogenic shock (CS) is scarce. Consecutive patients with CS were prospectively included from 2019 to 2021. The prognosis of patients with "low CVR" (i.
View Article and Find Full Text PDFRecent data suggest that uric acid (UA) might be an independent predictor of clinical outcomes following percutaneous coronary intervention (PCI). The predictive value of uric acid in patients undergoing PCI for chronic total occlusions (CTO) is unknown. We included patients with CTO who underwent PCI at our center in 2005 and 2012, with available uric acid levels before angiography.
View Article and Find Full Text PDFThe study sought to assess the procedural success of rotational atherectomy (RA) in coronary chronic total occlusion (CTO) and to investigate the in-hospital and one-year outcomes following RA. From 2015 to 2019, patients undergoing percutaneous coronary intervention for CTO (CTO PCI) were retrospectively included into the hospital database. The primary endpoint was procedural success.
View Article and Find Full Text PDFObjective: The study investigates the diagnostic and prognostic value of C-reactive protein (CRP) and procalcitonin (PCT) in patients with sepsis and septic shock.
Background: Limited data regarding the prognostic value of CRP and PCT during the course of sepsis or septic shock is available.
Methods: Consecutive patients with sepsis and septic shock from 2019 to 2021 were included monocentrically.