Publications by authors named "Jan Charles Biro"

Background: Shortly after the detection of the COVID virus in January 2020 the US Government introduced and enforced a series of restrictions to protect the elderly from a "deadly virus" and the "pandemic of the century". Persons who disagreed were silenced and punished.

Objective: In the 15th month of COVID epidemic (April 2021), we have access to sufficient statistical data and methods to better understand the nature, origin of the COVID pandemic.

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Background: All the information necessary for protein folding is supposed to be present in the amino acid sequence. It is still not possible to provide specific ab initio structure predictions by bioinformatical methods. It is suspected that additional folding information is present in protein coding nucleic acid sequences, but this is not represented by the known genetic code.

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An alternative model to the Watson & Crick (W&C) double DNA-spiral and the Pauling & Corey (P&C) triple spiral is presented. In this model: (1). the rotation axis of the polynucleotide chain is in the ribose ring; (2).

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Summary: An alternative method to TblastX has been developed. Nucleic acids in database and query sequences were translated into overlapping protein-like sequences (overlappingly translated sequences or OTSs) before searching with BlastP. Thus, each nucleic acid sequences is represented by a single 'protein like' sequence instead of three 'proteins' in different reading frames.

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