The effects of GH replacement therapy on cardiac morphology and function, exercise capacity and serum lipids in elderly patients with GH deficiency.

Objectives: To assess effects of GH replacement therapy on cardiac structure and function, exercise capacity as well as serum lipids in elderly patients with GH deficiency (GHD).

Patients And Methods: Thirty-one patients (six females, 25 males), aged 60-79 years (mean 68 years) with GHD on stable cortisone and thyroxine substitution were studied. All men with gonadotropin deficiency had testosterone and one woman had oestrogen replacement.

Laser Doppler perfusion monitoring of skin blood flow at different depths in finger and arm upon local heating.

The purpose of the study was to elucidate the vasodilatory response to local heating of the skin at two depths in two locations. To accomplish this, we measured skin blood flow in 12 healthy subjects using laser Doppler perfusion monitoring. A probe with two fibers separated 0.