Publications by authors named "Jan C Wohlsein"
Article Synopsis
- In steroid-responsive meningitis-arteritis (SRMA), a type of dog disease, special white blood cells called neutrophils cause inflammation in the brain and spinal cord.
- The study aimed to find out if these neutrophils can form something called NETs (neutrophil extracellular traps) in the fluids from sick dogs.
- Researchers found that NETs could be seen in some dogs with acute SRMA, but not in those recovering, suggesting that too many NETs could lead to more problems in dogs with this condition.
Steroid-responsive meningitis-arteritis (SRMA) occurs as an immune-mediated, inflammatory, and non-infectious disorder of juvenile and young-adult dogs. In principle, SRMA is divided into two clinical courses: during the typical acute form, dogs are presented with fever, cervical hyperaesthesia, and reluctance to move. The more protracted form most probably emerges after insufficient immunosuppressive treatment or relapses, with additional neurologic deficits localized in the cervical and thoracolumbar spinal cord or multifocally.
View Article and Find Full Text PDFExtracellular traps (ETs) are DNA networks formed by immune cells to fight infectious diseases by catching and attacking pathogenic microorganisms. Uncontrolled ET formation or impaired ET clearance can cause tissue and organ damage. Steroid-responsive meningitis-arteritis (SRMA) represents an immune-mediated, presumably non-infectious, purulent leptomeningitis and fibrinoid-necrotizing arteritis and periarteritis of young-adult dogs.
View Article and Find Full Text PDFStreptococcus (S.) phocae subsp. phocae causes bronchopneumonia and septicemia in a variety of marine mammals.
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