Assembly of DNA-functionalized gold nanoparticles studied by UV/Vis-spectroscopy and dynamic light scattering.

The DNA mediated assembly of complementary DNA-functionalized gold nanoparticles (DNA-AuNP) was investigated by means of UV/Vis-spectroscopy and Dynamic Light Scattering (DLS). The melting temperature of the aggregates was determined to be T(m) = 31 degrees C. Characterization of the assembly at 20 degrees C, 25 degrees C and 30 degrees C showed a decrease of the initial assembly growth rate with increasing temperature.