Publications by authors named "Jan Bozensky"

The increase in obesity prevalence has been slowing down in numerous countries recently. WHO Europe has organized surveillance of childhood obesity (Childhood Obesity Surveillance Initiative, COSI) since 2008, which observed the prevalence of overweight and obesity of 6-9-year-old children is followed during this study and proved this result. The study Children's Health 2016 showed that after a period of the global increase of obesity until 2011, there was in the Czech Republic a period of certain stabilization, in which there weren´t major changes in weight.

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The increasing prevalence of obesity and its associated complications leads to the need to intensify its prevention and treatment. The treatment of obesity is currently based on lifestyle modification, which often fails in the long term. For the next decade, the long-term administration of anti-obesity drugs, i.

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Article Synopsis
  • Some moms got a pertussis vaccine while pregnant, and it might affect how their babies respond to vaccinations later on.
  • Researchers studied toddlers who got their booster shots to see if the vaccine made a difference in their immune response.
  • After the booster, both groups did well, but toddlers who didn't get the mom's vaccine showed higher levels of certain antibodies.*
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Childhood obesity is one of the most serious public health challenges of the 21st century. The problem is global and it is steadily affecting health care of many countries. Increase in obesity prevalence has been slowing down in numerous countries recently.

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Background: Inactivating mutations of the hypothalamic transcription factor singleminded1 (SIM1) have been shown as a cause of early-onset severe obesity. However, to date, the contribution of SIM1 mutations to the obesity phenotype has only been studied in a few populations. In this study, we screened the functional regions of SIM1 in severely obese children of Slovak and Moravian descent to determine if genetic variants within SIM1 may influence the development of obesity in these populations.

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Unlabelled: The objective was to evaluate the effects of a hypoallergenic (HA) formula supplemented with prebiotic galacto-oligosaccharides on the severity of atopic manifestations. A randomised clinical trial was conducted. The control group was infants, fed with hypoallergenic formula and without supplementation.

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