Consistency of patient-reported outcomes after cholecystectomy and their implications on current surgical practice: a prospective multicenter cohort study.

Background: Persistent postoperative pain (up to 41 %) and significant practice variation necessitate better patient selection for cholecystectomy. Patient-reported outcome measures (PROMs) are nowadays known to serve as a tool for better patient selection, although variability within these subjective outcomes may be a point for debate. This study determines associations of both the preoperative pain and patient characteristics with PROMs at 24 weeks after cholecystectomy.

Biopsychosocial predictors of sexual function and quality of sexual life: a study among patients with colorectal cancer.

Objective: A low sexual function (SF) has been reported in patients with colorectal cancer. However, research often focusses on clinical predictors of SF, hereby omitting patients' subjective evaluation of SF [i.e.

[Population screening: there are no certainties].

Massive investments are being made for research into the prevention and reduction of risks and diseases. False-positive outcomes from screening investigations result in fear in a substantial number of patients, and are expensive for society as a whole. Screening for breast cancer has little or no impact on breast-cancer mortality; rather, the negative side-effects of false-positive outcomes of breast cancer screening are a serious problem.

Depressive symptoms are a risk factor for all-cause mortality: results from a prospective population-based study among 3,080 cancer survivors from the PROFILES registry.

Background: The goal of this large prospective population-based study was to examine the association between depressive symptoms and all-cause mortality among cancer survivors up to 10 years post-diagnosis.

Methods: All currently alive individuals diagnosed with endometrial or colorectal cancer (CRC) between 1998 and 2007 or with lymphoma or multiple myeloma between 1999 and 2008, as registered in the Eindhoven Cancer Registry, received a questionnaire on depressive symptoms (Hospital Anxiety and Depression Scale (HADS)) in 2008 or 2009, respectively; 69 % (n = 3,080) responded. Survival status was obtained from the Central Bureau for Genealogy.

Second primary cancers in subsites of colon and rectum in patients with previous colorectal cancer.

Background: Compared with the general population, patients with a previous colorectal cancer are at higher risk for a second colorectal cancer, but detailed risk analysis by subsite is scarce.

Objective: Our goal was to investigate the risk of a second cancer in relation to subsite as a basis for planning surveillance strategies.

Design, Setting, And Patients: This was a retrospective analysis of a prospectively designed, population-based cancer registry (The Netherlands Cancer Registry).

The preoperative sexual functioning and quality of sexual life in colorectal cancer: a study among patients and their partners.

Introduction: Even though the body of literature on sexual functioning is growing, information on the preoperative sexual functioning and the quality of sexual life after colorectal cancer is lacking. Research focusing on female patients and on partners is also rather scarce.

Aim: This cross-sectional study aimed to describe the preoperative sexual functioning, quality of sexual life, and relationship functioning for male and female colorectal cancer patients and their partners.

Type D personality is associated with increased comorbidity burden and health care utilization among 3080 cancer survivors.

Objective: Cancer survivors often report comorbid diseases, but there are individual differences in risk. Type D personality is a general propensity to psychological distress that is related to poor cardiovascular outcomes. In this study, we examined whether type D was also related to comorbidity burden and health care utilization among cancer survivors.

Review of recent studies on interventions for cognitive deficits in patients with cancer.

Research has demonstrated that patients with cancer experience cognitive deficits, often due to aggressive anticancer treatments. In this article, we critically review the interventional studies that have been conducted to investigate beneficial effects on cognitive function in cancer patients. Pharmacological agents that have been studied include psychostimulants, such as methylphenidate and modafinil, erythropoietin, and hormonal (supplement) treatments for patients who receive hormonal suppression therapy.

Type D (distressed) personality is associated with poor quality of life and mental health among 3080 cancer survivors.

Background: This study assessed the association between Type D personality (the conjoint effect of negative affectivity and social inhibition) and quality of life (QoL) and mental health of cancer survivors up to 10 years post-diagnosis.

Methods: All currently alive individuals diagnosed with endometrial or colorectal cancer between 1998 and 2007, or with lymphoma or multiple myeloma between 1999 and 2008 as registered in the Eindhoven Cancer Registry received a questionnaire on Type D personality (DS14), QoL (SF-36 or EORTC-QLQ-C30) and mental health (HADS).

Results: Of the 3080 survivors who responded (69%), 572 (19%) had a Type D personality.

The Patient Reported Outcomes Following Initial treatment and Long term Evaluation of Survivorship registry: scope, rationale and design of an infrastructure for the study of physical and psychosocial outcomes in cancer survivorship cohorts.

'Patient Reported Outcomes Following Initial treatment and Long term Evaluation of Survivorship (PROFILES)' is a registry for the study of the physical and psychosocial impact of cancer and its treatment from a dynamic, growing population-based cohort of both short and long-term cancer survivors. PROFILES contains a large web-based component and are linked directly to clinical data from the population-based Eindhoven cancer registry. This paper describes the rationale and design of PROFILES.

Risk factors for neurological deficiency one year after blunt-induced traumatic cervical fracture.

Background/aims: Little is known about the risk factors of neurological deficiency after blunt cervical fracture. This study was performed to identify factors predicting neurological deficiency after blunt cervical fracture.

Methods: Within our Level I Trauma Center, we performed a retrospective case-control study.

Risk factors predicting mortality after blunt traumatic cervical fracture.

Objective: Risk factors for mortality after blunt cervical trauma have received little attention within the literature. Therefore, we performed a study, to determine which factors are associated with mortality in patients with blunt cervical trauma.

Study Design: A retrospective study of 88 trauma patients, with cervical fractures, who were admitted to the emergency department of the St.

The patient's perspective of the quality of breast cancer care. The development of an instrument to measure quality of care through focus groups and concept mapping with breast cancer patients.

Quality of care is often described by professionals. However, in this study breast cancer patients participated in developing an instrument that reflects quality of care from the patient's perspective. Through focus groups and concept mapping patients' ideas on determinants of good quality of care were generated and categorised according to similarity and importance.