Publications by authors named "Jan A Sidler"
Aims Of The Study: We aimed to assess a potential association of iron status with mortality and morbidity of inpatients with systemic inflammation.
Methods: This was a single centre prospective observational study. From April 2014 to October 2014, all consecutive medical inpatients aged >=18 years with a C-reactive protein value >5 mg/l on hospital admission were eligible for the study.
Article Synopsis
- The study investigates the impact of low-dose acetylsalicylic acid (aspirin) on mortality rates in patients with Staphylococcus aureus bloodstream infections compared to those with Escherichia coli infections.
- A cohort of 838 S. aureus and 602 E. coli infection episodes was analyzed, revealing that 12.1% of patients with S. aureus who took acetylsalicylic acid died within 30 days, compared to 27.4% of those who did not, suggesting a significant reduction in mortality.
- In contrast, there was no significant mortality benefit observed in patients with E. coli infections taking acetylsalicylic acid, indicating a targeted effect for S. aureus
Objective: Little is known about optimal management of prosthetic vascular graft infections, which are a rare but serious complication associated with graft implants. The goal of this study was to compare and characterize these infections with respect to the location of the graft and to identify factors associated with outcome.
Methods: This was a retrospective study over more than a decade at a tertiary care university hospital that has an established multidisciplinary approach to treating graft infections.
Most hospital-acquired infections arise from colonising bacteria. Intensive care patients and immunocompromised individuals are at highest risk for microbial invasion and subsequent infection due to multiple invasive procedures in addition to frequent application of chemotherapeutics and presence of poor microperfusion leading to mucosal disruption. In this narrative review, we summarise the literature on bacterial colonisation in intensive care patients, in particular the epidemiology, the clinical impact and respective infection control strategies of three pathogens, i.
View Article and Find Full Text PDFBackground: Viral nosocomial infections (NIs) in children are common and most frequently affect the gastrointestinal or respiratory tract. Few studies are dedicated to this topic. We aimed to determine incidence and characteristics of these specific viral NIs at our hospital.
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