Publications by authors named "Jamuna Buchanan"
Cytomegalovirus, one of the most common congenital viruses in neonates, is represented within the TORCH acronym, which signifies its ability to be transmitted vertically to the fetus during maternal infection. Despite advances in prenatal diagnostics, CMV is still the leading cause of congenital infection in neonates, with a 0.64% prevalence.
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- This study aimed to examine how serum biomarkers related to brain injury change during chronic foetal hypoxia, comparing levels in fetuses with normal and reduced oxygen delivery.
- Mid-gestation fetal sheep were used in a controlled environment to replicate intrauterine conditions, where the levels of Myelin Basic Protein and Glial Fibrillary Acidic Protein were measured over time.
- Results showed no significant differences in the serum levels of these biomarkers between the normal and hypoxic groups, suggesting that brain development issues in fetuses with chronic hypoxia may arise from disrupted developmental processes rather than direct brain injury.