Vitamin D Supplementation May Prevent or Treat Deficiency After Total Knee Arthroplasty: A Retrospective Cohort Analysis.

Background: Vitamin D deficiency is associated with poorer functional outcomes and increased complication rates after total knee arthroplasty (TKA). Yet, there is no longer term study evaluating vitamin D levels and supplementation after TKA. Our study aimed to compare quantitative vitamin D levels and supplementation regimens after TKA stratified by patient sex and race.

An evaluation of the usability and durability of 3D printed versus standard suture materials.

The capability to produce suture material using three-dimensional (3D) printing technology may have applications in remote health facilities where rapid restocking of supplies is not an option. This is a feasibility study evaluating the usability of 3D-printed sutures in the repair of a laceration wound when compared with standard suture material. The 3D-printed suture material was manufactured using a fused deposition modelling 3D printer and nylon 3D printing filament.

Association of freeze-dried plasma with 24-h mortality among trauma patients at risk for hemorrhage.

Background: Blood products form the cornerstone of contemporary hemorrhage control but are limited resources. Freeze-dried plasma (FDP), which contains coagulation factors, is a promising adjunct in hemostatic resuscitation. We explore the association between FDP alone or in combination with other blood products on 24-h mortality.

Age, Sex, and Education Level Predict Telehealth Engagement in Total Joint Arthroplasty Patients.

Background: Racial and other demographic predictors of total joint arthroplasty (TJA) telehealth engagement since the onset of the COVID-19 pandemic remain unclear. The purpose of the current study was to elucidate this relationship.

Methods: A retrospective, cross-sectional study on 732 primary TJA patients was conducted within a single hospital system from March 2020-December 2021 (during the pandemic).

Fecal Impairment Framework, A New Conceptual Framework for Assessing Fecal Contamination in Recreational Waters.

Fecal pollution of surface water is a pervasive problem that negatively affects waterbodies concerning both public health and ecological functions. Current assessment methods monitor fecal indicator bacteria (FIB) to identify pollution sources using culture-based quantification and microbial source tracking (MST). These types of information assist stakeholders in identifying likely sources of fecal pollution, prioritizing them for remediation, and choosing appropriate best management practices.

Bone Cement Fumes Generated in Laminar Airflow Versus Conventionally Ventilated Operating Rooms: Does the Mixing System Matter?

Background: Bone cement is commonly utilized in a variety of orthopaedic procedures and contains methylmethacrylate (MMA) monomer. MMA is a colorless, clear, flammable liquid of intense odor. Its vapor concentration in the immediate breathing zone can vary considerably in the operative setting and, in higher concentrations, can become an occupational health hazard.

Frequency and degradation of SARS-CoV-2 markers N1, N2, and E in sewage.

Coronavirus disease 2019 (COVID-19) is an infectious disease that is mainly spread through aerosolized droplets containing severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and is excreted in feces by infected individuals. Sewage surveillance has been applied widely to obtain data on the prevalence of COVID-19 in whole communities. We used SARS-CoV-2 gene targets N1, N2, and E to determine the prevalence of COVID-19 at both municipal and building levels.

A Total Knee Arthroplasty Preoperative Optimization Program Managed by an Advanced Practice Provider (Physician Assistant) Decreases Complications and Cost: A Pilot Study.

Background: Studies have shown that optimizing modifiable risk factors leads to improved outcomes, with decreased lengths of stay (LOS), readmissions, complications, and hospital costs. Our goal was to demonstrate that use of an advanced practice provider, physician assistant (PA), within an orthopaedic practice would support these outcomes.

Methods: A preoperative optimization program managed by a PA was instituted at an academic medical center.

Using watershed characteristics to enhance fecal source identification.

Fecal pollution is one of the most prevalent forms of pollution affecting waterbodies worldwide, threatening public health and negatively impacting aquatic environments. Microbial source tracking (MST) applies polymerase chain reaction (PCR) technology to help identify the source of fecal pollution. In this study, we combine spatial data for two watersheds with general and host-associated MST markers to target human (HF183/BacR287), bovine (CowM2), and general ruminant (Rum2Bac) sources.

Quality and Perceived Usefulness of Patient-Submitted Store-and-Forward Teledermatology Images.

Importance: Patient-submitted images vary considerably in quality and usefulness. Studies that characterize patient-submitted images in a real-life setting are lacking.

Objective: To evaluate the quality and perceived usefulness of patient-submitted images as determined by dermatologists and characterize agreement of their responses.

What's Love Got to Do With It: Teaching the Next Generation of Nurses.

Many professional medical and nursing organizations call for the reform and revision of formal nursing education. As nursing faculty work to prepare the next generations of nurses, the model of Relationship-Based Care is an ideal infrastructure for curriculum design. This paper responds to the call for transforming nursing education with a model that includes love, Relationship-Based Care, the IE Model of Change, and an academic-practice partnership.

Lumbopelvic postural differences in adolescent idiopathic scoliosis: A pilot study.

Background: A primary etiology of adolescent idiopathic scoliosis (AIS) is currently unknown, but poor postural control of the spinal extensor musculature has been identified as an AIS risk factor. Identifiable postural differences would aid in advancing the precise postural behaviors that should be modified during Physiotherapy Scoliosis Specific Exercise (PSSE) to help limit the progression of AIS.

Research Question: Are there any determinable differences in lumbopelvic posture or range of motion between subjects with AIS and controls?

Methods: This prospective cohort pilot study consisted of 53 subjects (27 AIS and 26 control) aged 11-17 years.

Effects of coagulant morphology and chemical properties on soluble reactive phosphate removal in corn ethanol wastewater.

As ethanol production continues to rise around the world, and wastewater discharge requirements for phosphorus become more stringent, it is important that phosphorus removal technologies are evaluated on ethanol wastewater streams. In this study, five coagulating agents with distinct characteristics were evaluated for their soluble reactive phosphate (SRP) removal performance on both a synthetic wastewater sample and a wastewater sample collected from a corn ethanol manufacturer. All coagulants demonstrated a positive correlation between coagulant dose and percent removal of SRP on both samples.

Valuation of digital goods during the coronavirus outbreak in the United States.

We examine how the Coronavirus pandemic affected consumer valuation of digital services. Governments responded to the pandemic with various forms of lockdowns and social distancing, leading to increased dependence on digital services for work, social engagement, and leisure activities. We identify consumer valuations through surveys where respondents express their reservation prices for digital services such as email, search, and social media.

Whether Gametophytes are Reduced or Unreduced in Angiosperms Might Be Determined Metabolically.

In angiosperms, meiotic failure coupled with the formation of genetically unreduced gametophytes in ovules (apomeiosis) constitute major components of gametophytic apomixis. These aberrant developmental events are generally thought to be caused by mutation. However, efforts to locate the responsible mutations have failed.

Mercury methylation potential in a sand dune on Lake Michigan's eastern shoreline.

Lake Michigan hosts the largest freshwater sand dune system in the world and is economically important for the fishery industry and tourism. Due to industrial pollution and atmospheric mercury (Hg) deposition, toxic levels of methylmercury (MeHg) have been found in the Lake biota, but little information is known regarding MeHg sources and Hg methylation potential in the shoreline sand dunes. We conducted anaerobic incubation experiments with beach sands collected from Ludington, Michigan, and examined the effects of organic carbon substrate addition, inorganic nitrogen, and mineral magnetite on Hg methylation.

Bromo-spiroisoxazoline Alkaloids, Including an Isoserine Peptide, from the Caribbean Marine Sponge .

Three new bromotyrosine spiroisoxazoline alkaloids, lacunosins A and B ( and ) and desaminopurealin (), were isolated from a MeOH extract of the marine sponge that showed modest α-chymotrypsin inhibitory activity. The structures of - share the spirocyclohexadienyl-isoxazoline ring system found in purealidin-R and several other Verongid sponge secondary metabolites. Compounds and are coupled to a glycine and an isoserine methyl ester, respectively.

Effect of copper salts on hydrothermal oxidative decarboxylation: a study of phenylacetic acid.

Decarboxylation of carboxylic acids is favored under hydrothermal conditions, and can be influenced by dissolved metals. Here, we use phenylacetic acid as a model compound to study its hydrothermal decarboxylation in the presence of copper(ii) salts but no O. Our results showed a strong oxidizing role of copper in facilitating oxidative decarboxylation.

Temperature sensitivity of mineral-enzyme interactions on the hydrolysis of cellobiose and indican by β-glucosidase.

Extracellular enzymes are mainly responsible for depolymerizing soil organic matter (SOM) in terrestrial ecosystems, and soil minerals are known to affect enzyme activity. However, the mechanisms and the effects of mineral-enzyme interactions on enzymatic degradation of organic matter remain poorly understood. In this study, we examined the adsorption of fungal β-glucosidase enzyme on minerals and time-dependent changes of enzymatic reactivity, measured by the degradation of two organic substrates (i.

Synergistic Anti- Activity of Bengazole A in the Presence of Bengamide A †.

Bengazoles A⁻G from the marine sponge sp. exhibit potent in vitro antifungal activity against spp. and other pathogenic fungi.

Erythema ab igne in patients with sickle cell disease.

Erythema ab igne (EAI) is an asymptomatic dermatosis caused by prolonged exposure to localized heat. Affected areas have net-like hyperpigmentation that may resemble more serious conditions such as livedo racemosa or vasculitis. We report three cases of EAI in pediatric sickle cell disease (SCD) patients who were initially suspected of having a more severe, life-threatening disorder before Dermatology was consulted.

ESCAPE to Reality, Post-Trial Outcomes in an ESCAPE Centre: A Retrospective Case-Control Study.

Introduction: The Royal Victoria Hospital, Belfast provides the regional neuroendovascular service for Northern Ireland and was an enrolling centre for the ESCAPE endovascular stroke trial. Our aim was to assess outcomes for patients presenting with acute stroke following discontinuation of trial enrolment at our centre.

Methods: We collected data on all patients presenting with acute stoke between Nov-1st-2014 and Oct-31st-2015 who received endovascular treatment or received IV thrombolysis (IV-tPA) alone.